Gene detail

HMPREF9475_RS05255

Histidine kinase, Hybrid

[Clostridium] symbiosum WAL-14673 · GCF_000189615

ClassHKTypeHybridLength710 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000189615#HMPREF9475_RS05255Stable P2CS identifier used across views.
GenomeGCF_000189615Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_0750624Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_003507099.1 · MIST4 HMPREF9475_RS05255RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length710 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage299 / 710 aa (42.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa710 aa
HisKA: 335-400 aa (66 aa)1HATPase_c: 447-564 aa (118 aa)2Response_reg: 589-703 aa (115 aa)3
Domain-by-domain annotation3 items
1 HisKA#1
335-400 aa · 66 aa · 9.3% of protein
Raw tokenHisKA:335:0.00000000000000311:400:66:64
2 HATPase_c#2
447-564 aa · 118 aa · 16.6% of protein
Raw tokenHATPase_c:447:1.21e-28:564:119:109
3 Response_reg#3
589-703 aa · 115 aa · 16.2% of protein
Raw tokenResponse_reg:589:4.73e-28:703:115:111
  • Raw architecture: HisKA:335:0.00000000000000311:400:66:64#HATPase_c:447:1.21e-28:564:119:109#Response_reg:589:4.73e-28:703:115:111
  • Domain description: 1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000189615::NZ_GL834358.1::G00021
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span187201-189333Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9475_01031RefSeq proteinWP_003507099.1
Context group IDGCF_000189615::NZ_GL834358.1::G00021
Context members
HMPREF9475_RS05255
Partner locus tags
HMPREF9475_RS05255
Partner old locus tags
HMPREF9475_01031
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_003507099.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9475_RS05255Primary locus identifier stored in the genes table.
Old locus tagHMPREF9475_01031Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834358.1Sequence record reported by the local genomic context database.
Genomic interval187 201-189 333 nt2 133 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span187 201-189 333 ntGCF_000189615::NZ_GL834358.1::G00021

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189615::NZ_GL834358.1::G00021

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834358.1All displayed genes belong to this local TCS context.
Neighborhood span187 201-189 333 nt2 133 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
187 201 nt189 333 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0750624Run 6 · HK · 2 sequences
Representative sequenceGCF_000189615#HMPREF9475_RS05255The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0750624

Simplified PFAM architecture for HKOC_0750624

PFAM domain coverage: 298 / 710 aa (42.0%)

1 aa710 aa
HisKA: 335-400 aaHisKAHATPase_c: 447-563 aaHATPase_cResponse_reg: 589-703 aaResponse_reg
HisKAHATPase_cResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg
  • Raw architecture: HisKA[335-400] | HATPase_c[447-563] | Response_reg[589-703]
  • Domain count: 3
  • Matched identifier: HKOC_0750624
  • Positioned domains: HisKA 335-400 ; HATPase_c 447-563 ; Response_reg 589-703
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189615#HMPREF9475_RS05255

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 741 · GCF_000189615
AssemblyClos_symb_WAL_14673_V2 · Scaffoldhaploid
Genome composition4 916 964 bp · 48,0% GC[Clostridium] symbiosum WAL-14673
Signal transduction countsGenes 109 · HK 55 · RR 50CheA 0 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key