Gene detail

HMPREF9475_RS05165

Histidine kinase, Hybrid

[Clostridium] symbiosum WAL-14673 · GCF_000189615

ClassHKTypeHybridLength1053 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000189615#HMPREF9475_RS05165Stable P2CS identifier used across views.
GenomeGCF_000189615Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_0257008Run 6 · 4 sequences · id 100% · cov 80% · representative
External referencesWP_003507067.1 · MIST4 HMPREF9475_RS05165RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_3HisKAHATPase_cResponse_reg
Protein length1053 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage425 / 1053 aa (40.4%)Merged over positioned domains only.
Domain description2 PAS_3,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1053 aa
PAS_3: 33-101 aa (69 aa)1PAS_3: 188-246 aa (59 aa)2HisKA: 671-735 aa (65 aa)3HATPase_c: 784-898 aa (115 aa)4Response_reg: 929-1045 aa (117 aa)5
Domain-by-domain annotation5 items
1 PAS_3#1
33-101 aa · 69 aa · 6.6% of protein
Raw tokenPAS_3:33:0.00000858:101:78:89
2 PAS_3#2
188-246 aa · 59 aa · 5.6% of protein
Raw tokenPAS_3:188:0.0000000000714:246:60:89
3 HisKA#3
671-735 aa · 65 aa · 6.2% of protein
Raw tokenHisKA:671:0.0000000000000078:735:65:64
4 HATPase_c#4
784-898 aa · 115 aa · 10.9% of protein
Raw tokenHATPase_c:784:8.74e-31:898:116:109
5 Response_reg#5
929-1045 aa · 117 aa · 11.1% of protein
Raw tokenResponse_reg:929:3.19e-26:1045:117:111
  • Raw architecture: PAS_3:33:0.00000858:101:78:89#PAS_3:188:0.0000000000714:246:60:89#HisKA:671:0.0000000000000078:735:65:64#HATPase_c:784:8.74e-31:898:116:109#Response_reg:929:3.19e-26:1045:117:111
  • Domain description: 2 PAS_3,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000189615::NZ_GL834358.1::G00019
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span168162-171323Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9475_01013RefSeq proteinWP_003507067.1
Context group IDGCF_000189615::NZ_GL834358.1::G00019
Context members
HMPREF9475_RS05165
Partner locus tags
HMPREF9475_RS05165
Partner old locus tags
HMPREF9475_01013
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_003507067.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9475_RS05165Primary locus identifier stored in the genes table.
Old locus tagHMPREF9475_01013Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834358.1Sequence record reported by the local genomic context database.
Genomic interval168 162-171 323 nt3 162 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span168 162-171 323 ntGCF_000189615::NZ_GL834358.1::G00019

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189615::NZ_GL834358.1::G00019

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834358.1All displayed genes belong to this local TCS context.
Neighborhood span168 162-171 323 nt3 162 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
168 162 nt171 323 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0257008Run 6 · HK · 4 sequences
Representative sequenceGCF_000189615#HMPREF9475_RS05165The current gene is the representative for this cluster.
PFAM architecturePAS_3 + HisKA + HATPase_c + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0257008

Simplified PFAM architecture for HKOC_0257008

PFAM domain coverage: 381 / 1053 aa (36.2%)

1 aa1053 aa
PAS_3: 160-244 aaPAS_3HisKA: 671-735 aaHisKAHATPase_c: 784-898 aaHATPase_cResponse_reg: 929-1044 aaResponse_reg
PAS_3HisKAHATPase_cResponse_reg
  • Simplified architecture: PAS_3 + HisKA + HATPase_c + Response_reg
  • Raw architecture: PAS_3[160-244] | HisKA[671-735] | HATPase_c[784-898] | Response_reg[929-1044]
  • Domain count: 4
  • Matched identifier: HKOC_0257008
  • Positioned domains: PAS_3 160-244 ; HisKA 671-735 ; HATPase_c 784-898 ; Response_reg 929-1044
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189615#HMPREF9475_RS05165

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 741 · GCF_000189615
AssemblyClos_symb_WAL_14673_V2 · Scaffoldhaploid
Genome composition4 916 964 bp · 48,0% GC[Clostridium] symbiosum WAL-14673
Signal transduction countsGenes 109 · HK 55 · RR 50CheA 0 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key