1 HAMP#1
183-252 aa · 70 aa · 14.1% of protein
Raw token
HAMP:183:4.27e-16:252:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9475_RS01115
Histidine kinase, Classic
[Clostridium] symbiosum WAL-14673 · GCF_000189615
ClassHKTypeClassicLength495 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189615#HMPREF9475_RS01115Stable P2CS identifier used across views.
GenomeGCF_000189615Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length495 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage249 / 495 aa (50.3%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa495 aa
Domain-by-domain annotation3 items
2 HisKA#2
266-330 aa · 65 aa · 13.1% of protein
Raw token
HisKA:266:2.49e-16:330:65:643 HATPase_c#3
377-490 aa · 114 aa · 23.0% of protein
Raw token
HATPase_c:377:2.95e-32:490:114:109- Raw architecture: HAMP:183:4.27e-16:252:70:69#HisKA:266:2.49e-16:330:65:64#HATPase_c:377:2.95e-32:490:114:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000189615::NZ_GL834357.1::G00007
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span277237-279410Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9475_00219RefSeq proteinWP_003498065.1
Context group ID
GCF_000189615::NZ_GL834357.1::G00007Context members
HMPREF9475_RS01115HMPREF9475_RS01120
Partner locus tags
HMPREF9475_RS01115HMPREF9475_RS01120
Partner old locus tags
HMPREF9475_00219HMPREF9475_00220
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003498065.1Primary protein accession used for annex mappings.
UniProt accessionE7GI40Primary UniProt accession resolved in the annex database.
UniProt IDE7GI40_CLOS6Display identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9475_RS01115Primary locus identifier stored in the genes table.
Old locus tagHMPREF9475_00219Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834357.1Sequence record reported by the local genomic context database.
Genomic interval277 237-278 724 nt1 488 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span277 237-279 410 ntGCF_000189615::NZ_GL834357.1::G00007
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000189615::NZ_GL834357.1::G00007Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834357.1All displayed genes belong to this local TCS context.
Neighborhood span277 237-279 410 nt2 174 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
277 237 nt279 410 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9475_RS01115GCF_000189615#HMPREF9475_RS01115
HKClassicCurrent focus
277 237-278 724 nt · Forward (+)
HMPREF9475_RS01120GCF_000189615#HMPREF9475_RS01120
RROmpR
278 721-279 410 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000189595#HMPREF9474_RS02930Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1504326
Simplified PFAM architecture for HKOC_1504326
PFAM domain coverage: 229 / 495 aa (46.3%)
1 aa495 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[200-252] | HisKA[265-329] | HATPase_c[378-488]
- Domain count: 3
- Matched identifier: HKOC_1504326
- Positioned domains: HAMP 200-252 ; HisKA 265-329 ; HATPase_c 378-488
Cluster members and taxonomy
Representative gene: GCF_000189595#HMPREF9474_RS02930
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 742 741 · GCF_000189615
AssemblyClos_symb_WAL_14673_V2 · Scaffoldhaploid
Genome composition4 916 964 bp · 48,0% GC[Clostridium] symbiosum WAL-14673
Signal transduction countsGenes 109 · HK 55 · RR 50CheA 0 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium
Related genes
Preview from the same derived genome key