Gene detail

HMPREF9474_RS03380

Histidine kinase, Classic

[Clostridium] symbiosum WAL-14163 · GCF_000189595

ClassHKTypeClassicLength374 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189595#HMPREF9474_RS03380Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_2657528Run 6 · 71 sequences · id 100% · cov 80% · representative
External referencesWP_003498252.1 · E7GIA9 · MIST4 HMPREF9474_RS03380RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length374 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage180 / 374 aa (48.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa374 aa
HisKA: 146-214 aa (69 aa)1HATPase_c: 258-368 aa (111 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
146-214 aa · 69 aa · 18.4% of protein
Raw tokenHisKA:146:0.00000000000152:214:69:64
2 HATPase_c#2
258-368 aa · 111 aa · 29.7% of protein
Raw tokenHATPase_c:258:1.73e-25:368:112:109
  • Raw architecture: HisKA:146:0.00000000000152:214:69:64#HATPase_c:258:1.73e-25:368:112:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000189595::NZ_GL834305.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span799848-801675Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_00652RefSeq proteinWP_003498252.1
Context group IDGCF_000189595::NZ_GL834305.1::G00013
Context members
HMPREF9474_RS03380HMPREF9474_RS03385
Partner locus tags
HMPREF9474_RS03380HMPREF9474_RS03385
Partner old locus tags
HMPREF9474_00652HMPREF9474_00653
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003498252.1Primary protein accession used for annex mappings.
UniProt accessionE7GIA9Primary UniProt accession resolved in the annex database.
UniProt IDE7GIA9_CLOS6Display identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9474_RS03380Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_00652Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834305.1Sequence record reported by the local genomic context database.
Genomic interval799 848-800 972 nt1 125 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span799 848-801 675 ntGCF_000189595::NZ_GL834305.1::G00013

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189595::NZ_GL834305.1::G00013

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834305.1All displayed genes belong to this local TCS context.
Neighborhood span799 848-801 675 nt1 828 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
799 848 nt801 675 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9474_RS03385GCF_000189595#HMPREF9474_RS03385
RROmpR

800 962-801 675 nt · Forward (+)

Old locus HMPREF9474_00653RefSeq WP_003498254.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2657528Run 6 · HK · 71 sequences
Representative sequenceGCF_000189595#HMPREF9474_RS03380The current gene is the representative for this cluster.
PFAM architectureDUF4118 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2657528

Simplified PFAM architecture for HKOC_2657528

PFAM domain coverage: 287 / 374 aa (76.7%)

1 aa374 aa
DUF4118: 25-134 aaDUF4118HisKA: 147-213 aaHisKAHATPase_c: 259-368 aaHATPase_c
DUF4118HisKAHATPase_c
  • Simplified architecture: DUF4118 + HisKA + HATPase_c
  • Raw architecture: DUF4118[25-134] | HisKA[147-213] | HATPase_c[259-368]
  • Domain count: 3
  • Matched identifier: HKOC_2657528
  • Positioned domains: DUF4118 25-134 ; HisKA 147-213 ; HATPase_c 259-368
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189595#HMPREF9474_RS03380

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key