Gene detail

HMPREF9474_RS22980

Histidine kinase, Classic

[Clostridium] symbiosum WAL-14163 · GCF_000189595

ClassHKTypeClassicLength450 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000189595#HMPREF9474_RS22980Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_1962199Run 6 · 20 sequences · id 100% · cov 80% · representative
External referencesWP_003504953.1 · E7GU59 · MIST4 HMPREF9474_RS22980RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length450 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage195 / 450 aa (43.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa450 aa
HisKA: 209-282 aa (74 aa)1HATPase_c: 329-449 aa (121 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
209-282 aa · 74 aa · 16.4% of protein
Raw tokenHisKA:209:0.0000000000000188:282:74:64
2 HATPase_c#2
329-449 aa · 121 aa · 26.9% of protein
Raw tokenHATPase_c:329:1.26e-28:449:121:109
  • Raw architecture: HisKA:209:0.0000000000000188:282:74:64#HATPase_c:329:1.26e-28:449:121:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000189595::NZ_GL834322.1::G00061
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span41654-43006Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_04454RefSeq proteinWP_003504953.1
Context group IDGCF_000189595::NZ_GL834322.1::G00061
Context members
HMPREF9474_RS22980
Partner locus tags
HMPREF9474_RS22980
Partner old locus tags
HMPREF9474_04454
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003504953.1Primary protein accession used for annex mappings.
UniProt accessionE7GU59Primary UniProt accession resolved in the annex database.
UniProt IDE7GU59_CLOS6Display identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9474_RS22980Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_04454Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834322.1Sequence record reported by the local genomic context database.
Genomic interval41 654-43 006 nt1 353 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span41 654-43 006 ntGCF_000189595::NZ_GL834322.1::G00061

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189595::NZ_GL834322.1::G00061

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834322.1All displayed genes belong to this local TCS context.
Neighborhood span41 654-43 006 nt1 353 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
41 654 nt43 006 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1962199Run 6 · HK · 20 sequences
Representative sequenceGCF_000189595#HMPREF9474_RS22980The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1962199

Simplified PFAM architecture for HKOC_1962199

PFAM domain coverage: 192 / 450 aa (42.7%)

1 aa450 aa
HisKA: 210-282 aaHisKAHATPase_c: 330-448 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[210-282] | HATPase_c[330-448]
  • Domain count: 2
  • Matched identifier: HKOC_1962199
  • Positioned domains: HisKA 210-282 ; HATPase_c 330-448
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189595#HMPREF9474_RS22980

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key