1 HAMP#1
154-223 aa · 70 aa · 15.9% of protein
Raw token
HAMP:154:0.000000000778:223:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9474_RS00525
Histidine kinase, Classic
[Clostridium] symbiosum WAL-14163 · GCF_000189595
ClassHKTypeClassicLength441 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189595#HMPREF9474_RS00525Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length441 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage210 / 441 aa (47.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa441 aa
Domain-by-domain annotation3 items
2 HisKA#2
238-288 aa · 51 aa · 11.6% of protein
Raw token
HisKA:238:0.000000118:288:51:643 HATPase_c#3
347-435 aa · 89 aa · 20.2% of protein
Raw token
HATPase_c:347:0.0000000124:435:105:109- Raw architecture: HAMP:154:0.000000000778:223:70:69#HisKA:238:0.000000118:288:51:64#HATPase_c:347:0.0000000124:435:105:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000189595::NZ_GL834305.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span119462-121487Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_00094RefSeq proteinWP_003497174.1
Context group ID
GCF_000189595::NZ_GL834305.1::G00002Context members
HMPREF9474_RS00520HMPREF9474_RS00525
Partner locus tags
HMPREF9474_RS00520HMPREF9474_RS00525
Partner old locus tags
HMPREF9474_00093HMPREF9474_00094
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003497174.1Primary protein accession used for annex mappings.
UniProt accessionE7GGQ1Primary UniProt accession resolved in the annex database.
UniProt IDE7GGQ1_CLOS6Display identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9474_RS00525Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_00094Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834305.1Sequence record reported by the local genomic context database.
Genomic interval120 162-121 487 nt1 326 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span119 462-121 487 ntGCF_000189595::NZ_GL834305.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000189595::NZ_GL834305.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834305.1All displayed genes belong to this local TCS context.
Neighborhood span119 462-121 487 nt2 026 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
119 462 nt121 487 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9474_RS00520GCF_000189595#HMPREF9474_RS00520
RROmpR
119 462-120 169 nt · Forward (+)
HMPREF9474_RS00525GCF_000189595#HMPREF9474_RS00525
HKClassicCurrent focus
120 162-121 487 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000189595#HMPREF9474_RS00525The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2061476
Simplified PFAM architecture for HKOC_2061476
PFAM domain coverage: 112 / 441 aa (25.4%)
1 aa441 aa
HAMPHisKA
- Simplified architecture: HAMP + HisKA
- Raw architecture: HAMP[173-223] | HisKA[236-296]
- Domain count: 2
- Matched identifier: HKOC_2061476
- Positioned domains: HAMP 173-223 ; HisKA 236-296
Cluster members and taxonomy
Representative gene: GCF_000189595#HMPREF9474_RS00525
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium
Related genes
Preview from the same derived genome key