Gene detail

HMPREF9474_RS20005

Histidine kinase, Classic

[Clostridium] symbiosum WAL-14163 · GCF_000189595

ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000189595#HMPREF9474_RS20005Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_1747837Run 6 · 70 sequences · id 100% · cov 80% · representative
External referencesWP_003503824.1 · E7GSI8 · MIST4 HMPREF9474_RS20005RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage248 / 467 aa (53.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
HAMP: 169-238 aa (70 aa)1HisKA: 243-307 aa (65 aa)2HATPase_c: 353-465 aa (113 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
169-238 aa · 70 aa · 15.0% of protein
Raw tokenHAMP:169:0.000000000293:238:70:69
2 HisKA#2
243-307 aa · 65 aa · 13.9% of protein
Raw tokenHisKA:243:1.83e-17:307:65:64
3 HATPase_c#3
353-465 aa · 113 aa · 24.2% of protein
Raw tokenHATPase_c:353:7.71e-31:465:113:109
  • Raw architecture: HAMP:169:0.000000000293:238:70:69#HisKA:243:1.83e-17:307:65:64#HATPase_c:353:7.71e-31:465:113:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000189595::NZ_GL834317.1::G00054
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span87692-89095Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_03883RefSeq proteinWP_003503824.1
Context group IDGCF_000189595::NZ_GL834317.1::G00054
Context members
HMPREF9474_RS20005
Partner locus tags
HMPREF9474_RS20005
Partner old locus tags
HMPREF9474_03883
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003503824.1Primary protein accession used for annex mappings.
UniProt accessionE7GSI8Primary UniProt accession resolved in the annex database.
UniProt IDE7GSI8_CLOS6Display identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9474_RS20005Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_03883Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834317.1Sequence record reported by the local genomic context database.
Genomic interval87 692-89 095 nt1 404 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span87 692-89 095 ntGCF_000189595::NZ_GL834317.1::G00054

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189595::NZ_GL834317.1::G00054

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834317.1All displayed genes belong to this local TCS context.
Neighborhood span87 692-89 095 nt1 404 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
87 692 nt89 095 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1747837Run 6 · HK · 70 sequences
Representative sequenceGCF_000189595#HMPREF9474_RS20005The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1747837

Simplified PFAM architecture for HKOC_1747837

PFAM domain coverage: 218 / 467 aa (46.7%)

1 aa467 aa
HAMP: 194-237 aaHAMPHisKA: 243-307 aaHisKAHATPase_c: 356-464 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[194-237] | HisKA[243-307] | HATPase_c[356-464]
  • Domain count: 3
  • Matched identifier: HKOC_1747837
  • Positioned domains: HAMP 194-237 ; HisKA 243-307 ; HATPase_c 356-464
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189595#HMPREF9474_RS20005

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key