1 PAS_3#1
458-520 aa · 63 aa · 6.7% of protein
Raw token
PAS_3:458:0.0000302:520:64:89P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9474_RS05070
Histidine kinase, Hybrid
[Clostridium] symbiosum WAL-14163 · GCF_000189595
ClassHKTypeHybridLength939 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189595#HMPREF9474_RS05070Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Domain signature
Compact overview inferred from the domain field
PAS_3HisKAHATPase_cResponse_reg
Protein length939 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage364 / 939 aa (38.8%)Merged over positioned domains only.
Domain description1 PAS_3,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa939 aa
Domain-by-domain annotation4 items
2 HisKA#2
553-619 aa · 67 aa · 7.1% of protein
Raw token
HisKA:553:2.78e-17:619:67:643 HATPase_c#3
666-783 aa · 118 aa · 12.6% of protein
Raw token
HATPase_c:666:1.99e-30:783:118:1094 Response_reg#4
822-937 aa · 116 aa · 12.4% of protein
Raw token
Response_reg:822:1.43e-25:937:116:111- Raw architecture: PAS_3:458:0.0000302:520:64:89#HisKA:553:2.78e-17:619:67:64#HATPase_c:666:1.99e-30:783:118:109#Response_reg:822:1.43e-25:937:116:111
- Domain description: 1 PAS_3,1 HisKA,1 HATPase_c,1 Response_reg
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000189595::NZ_GL834306.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span293162-296857Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_00982RefSeq proteinWP_003498970.1
Context group ID
GCF_000189595::NZ_GL834306.1::G00020Context members
HMPREF9474_RS05065HMPREF9474_RS05070
Partner locus tags
HMPREF9474_RS05065HMPREF9474_RS05070
Partner old locus tags
HMPREF9474_00981HMPREF9474_00982
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003498970.1Primary protein accession used for annex mappings.
UniProt accessionE7GJ89Primary UniProt accession resolved in the annex database.
UniProt IDE7GJ89_CLOS6Display identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9474_RS05070Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_00982Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834306.1Sequence record reported by the local genomic context database.
Genomic interval294 038-296 857 nt2 820 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span293 162-296 857 ntGCF_000189595::NZ_GL834306.1::G00020
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000189595::NZ_GL834306.1::G00020Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834306.1All displayed genes belong to this local TCS context.
Neighborhood span293 162-296 857 nt3 696 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
293 162 nt296 857 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9474_RS05065GCF_000189595#HMPREF9474_RS05065
RROmpR
293 162-293 857 nt · Forward (+)
HMPREF9474_RS05070GCF_000189595#HMPREF9474_RS05070
HKHybridCurrent focus
294 038-296 857 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000189595#HMPREF9474_RS05070The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0341181
Simplified PFAM architecture for HKOC_0341181
PFAM domain coverage: 300 / 939 aa (31.9%)
1 aa939 aa
HisKAHATPase_cResponse_reg
- Simplified architecture: HisKA + HATPase_c + Response_reg
- Raw architecture: HisKA[553-619] | HATPase_c[666-783] | Response_reg[822-936]
- Domain count: 3
- Matched identifier: HKOC_0341181
- Positioned domains: HisKA 553-619 ; HATPase_c 666-783 ; Response_reg 822-936
Cluster members and taxonomy
Representative gene: GCF_000189595#HMPREF9474_RS05070
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium
Related genes
Preview from the same derived genome key