1 GAF#1
226-347 aa · 122 aa · 21.6% of protein
Raw token
GAF:226:0.0000193:347:134:133P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ESG_RS0114110
Histidine kinase, Classic
Escherichia coli TW11681 · GCF_000166595
ClassHKTypeClassicLength565 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000166595#ESG_RS0114110Stable P2CS identifier used across views.
GenomeGCF_000166595Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
GAFHis_kinaseHATPase_c
Protein length565 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage298 / 565 aa (52.7%)Merged over positioned domains only.
Domain description1 GAF,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa565 aa
Domain-by-domain annotation3 items
2 His_kinase#2
359-438 aa · 80 aa · 14.2% of protein
Raw token
His_kinase:359:1.17e-31:438:81:803 HATPase_c#3
456-551 aa · 96 aa · 17.0% of protein
Raw token
HATPase_c:456:0.0000000000377:551:103:109- Raw architecture: GAF:226:0.0000193:347:134:133#His_kinase:359:1.17e-31:438:81:80#HATPase_c:456:0.0000000000377:551:103:109
- Domain description: 1 GAF,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000166595::NZ_AELD01000023.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span20444-22890Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000166595::NZ_AELD01000023.1::G00013Context members
ESG_RS0114110ESG_RS0114115
Partner locus tags
ESG_RS0114110ESG_RS0114115
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_000544351.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagESG_RS0114110Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_AELD01000023.1Sequence record reported by the local genomic context database.
Genomic interval20 444-22 141 nt1 698 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span20 444-22 890 ntGCF_000166595::NZ_AELD01000023.1::G00013
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000166595::NZ_AELD01000023.1::G00013Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AELD01000023.1All displayed genes belong to this local TCS context.
Neighborhood span20 444-22 890 nt2 447 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
20 444 nt22 890 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ESG_RS0114110GCF_000166595#ESG_RS0114110
HKClassicCurrent focus
20 444-22 141 nt · Forward (+)
ESG_RS0114115GCF_000166595#ESG_RS0114115
RRLytTR
22 156-22 890 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000166595#ESG_RS0114110The current gene is the representative for this cluster.
PFAM architecture5TM-5TMR_LYT + GAF + His_kinase + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1234087
Simplified PFAM architecture for HKOC_1234087
PFAM domain coverage: 461 / 565 aa (81.6%)
1 aa565 aa
5TM-5TMR_LYTGAFHis_kinaseHATPase_c
- Simplified architecture: 5TM-5TMR_LYT + GAF + His_kinase + HATPase_c
- Raw architecture: 5TM-5TMR_LYT[28-192] | GAF[226-343] | His_kinase[359-438] | HATPase_c[456-553]
- Domain count: 4
- Matched identifier: HKOC_1234087
- Positioned domains: 5TM-5TMR_LYT 28-192 ; GAF 226-343 ; His_kinase 359-438 ; HATPase_c 456-553
Cluster members and taxonomy
Representative gene: GCF_000166595#ESG_RS0114110
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 913 088 · GCF_000166595
AssemblyASM16659v2 · Contighaploid
Genome composition5 305 843 bp · 50,5% GCEscherichia coli TW11681
Signal transduction countsGenes 68 · HK 32 · RR 35CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key