1 H-kinase_dim#1
165-226 aa · 62 aa · 11.2% of protein
Raw token
H-kinase_dim:165:1.54e-18:226:66:67P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ESG_RS01000000127820
Histidine kinase, CheA
Escherichia coli TW11681 · GCF_000166595
ClassHKTypeCheALength556 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000166595#ESG_RS01000000127820Stable P2CS identifier used across views.
GenomeGCF_000166595Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
H-kinase_dimHATPase_cCheW
Protein length556 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage328 / 556 aa (59.0%)Merged over positioned domains only.
Domain description1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa556 aa
Domain-by-domain annotation3 items
2 HATPase_c#2
273-410 aa · 138 aa · 24.8% of protein
Raw token
HATPase_c:273:1.31e-16:410:138:1093 CheW#3
415-542 aa · 128 aa · 23.0% of protein
Raw token
CheW:415:1.85e-29:542:134:138- Raw architecture: H-kinase_dim:165:1.54e-18:226:66:67#HATPase_c:273:1.31e-16:410:138:109#CheW:415:1.85e-29:542:134:138
- Domain description: 1 H-kinase_dim,1 HATPase_c,1 CheW
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000166595::NZ_AELD01000024.1::G00011
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span161689-163360Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000166595::NZ_AELD01000024.1::G00011Context members
ESG_RS01000000127820
Partner locus tags
ESG_RS01000000127820
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_001157795.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagESG_RS01000000127820Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_AELD01000024.1Sequence record reported by the local genomic context database.
Genomic interval161 689-163 360 nt1 672 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span161 689-163 360 ntGCF_000166595::NZ_AELD01000024.1::G00011
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000166595::NZ_AELD01000024.1::G00011Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AELD01000024.1All displayed genes belong to this local TCS context.
Neighborhood span161 689-163 360 nt1 672 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
161 689 nt163 360 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
ESG_RS01000000127820GCF_000166595#ESG_RS01000000127820
HKCheACurrent focus
161 689-163 360 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000166595#ESG_RS01000000127820The current gene is the representative for this cluster.
PFAM architectureCheY-binding + H-kinase_dim + HATPase_c + CheW4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1271851
Simplified PFAM architecture for HKOC_1271851
PFAM domain coverage: 391 / 556 aa (70.3%)
1 aa556 aa
CheY-bindingH-kinase_dimHATPase_cCheW
- Simplified architecture: CheY-binding + H-kinase_dim + HATPase_c + CheW
- Raw architecture: CheY-binding[63-125] | H-kinase_dim[163-226] | HATPase_c[274-410] | CheW[416-542]
- Domain count: 4
- Matched identifier: HKOC_1271851
- Positioned domains: CheY-binding 63-125 ; H-kinase_dim 163-226 ; HATPase_c 274-410 ; CheW 416-542
Cluster members and taxonomy
Representative gene: GCF_000166595#ESG_RS01000000127820
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 913 088 · GCF_000166595
AssemblyASM16659v2 · Contighaploid
Genome composition5 305 843 bp · 50,5% GCEscherichia coli TW11681
Signal transduction countsGenes 68 · HK 32 · RR 35CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key