1 HAMP#1
188-258 aa · 71 aa · 14.4% of protein
Raw token
HAMP:188:0.000000000367:258:71:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ESG_RS0102245
Histidine kinase, Classic
Escherichia coli TW11681 · GCF_000166595
ClassHKTypeClassicLength493 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000166595#ESG_RS0102245Stable P2CS identifier used across views.
GenomeGCF_000166595Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length493 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage247 / 493 aa (50.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa493 aa
Domain-by-domain annotation3 items
2 HisKA#2
262-328 aa · 67 aa · 13.6% of protein
Raw token
HisKA:262:0.00000000000723:328:67:643 HATPase_c#3
372-480 aa · 109 aa · 22.1% of protein
Raw token
HATPase_c:372:3.97e-28:480:110:109- Raw architecture: HAMP:188:0.000000000367:258:71:69#HisKA:262:0.00000000000723:328:67:64#HATPase_c:372:3.97e-28:480:110:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000166595::NZ_AELD01000006.1::G00036
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span19802-21956Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000166595::NZ_AELD01000006.1::G00036Context members
ESG_RS0102240ESG_RS0102245
Partner locus tags
ESG_RS0102240ESG_RS0102245
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000555740.1Primary protein accession used for annex mappings.
UniProt accessionA0A7I8YML3Primary UniProt accession resolved in the annex database.
UniProt IDA0A7I8YML3_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagESG_RS0102245Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_AELD01000006.1Sequence record reported by the local genomic context database.
Genomic interval20 475-21 956 nt1 482 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span19 802-21 956 ntGCF_000166595::NZ_AELD01000006.1::G00036
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000166595::NZ_AELD01000006.1::G00036Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AELD01000006.1All displayed genes belong to this local TCS context.
Neighborhood span19 802-21 956 nt2 155 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
19 802 nt21 956 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ESG_RS0102240GCF_000166595#ESG_RS0102240
RROmpR
19 802-20 482 nt · Forward (+)
ESG_RS0102245GCF_000166595#ESG_RS0102245
HKClassicCurrent focus
20 475-21 956 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000166595#ESG_RS0102245The current gene is the representative for this cluster.
PFAM architectureCusS + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1514867
Simplified PFAM architecture for HKOC_1514867
PFAM domain coverage: 399 / 493 aa (80.9%)
1 aa493 aa
CusSHAMPHisKAHATPase_c
- Simplified architecture: CusS + HAMP + HisKA + HATPase_c
- Raw architecture: CusS[8-181] | HAMP[208-257] | HisKA[263-327] | HATPase_c[372-481]
- Domain count: 4
- Matched identifier: HKOC_1514867
- Positioned domains: CusS 8-181 ; HAMP 208-257 ; HisKA 263-327 ; HATPase_c 372-481
Cluster members and taxonomy
Representative gene: GCF_000166595#ESG_RS0102245
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 913 088 · GCF_000166595
AssemblyASM16659v2 · Contighaploid
Genome composition5 305 843 bp · 50,5% GCEscherichia coli TW11681
Signal transduction countsGenes 68 · HK 32 · RR 35CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key