Gene detail

ESG_RS0107235

Histidine kinase, Classic

Escherichia coli TW11681 · GCF_000166595

ClassHKTypeClassicLength431 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000166595#ESG_RS0107235Stable P2CS identifier used across views.
GenomeGCF_000166595Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_2161294Run 6 · 772 sequences · id 100% · cov 80%
External referencesWP_000893580.1 · A0A1V3W2Z6 · MIST4 ESG_RS0107235RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PASHisKAHATPase_c
Protein length431 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage275 / 431 aa (63.8%)Merged over positioned domains only.
Domain description1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa431 aa
PAS: 98-194 aa (97 aa)1HisKA: 203-268 aa (66 aa)2HATPase_c: 313-424 aa (112 aa)3
Domain-by-domain annotation3 items
1 PAS#1
98-194 aa · 97 aa · 22.5% of protein
Raw tokenPAS:98:0.00000000000247:194:113:113
2 HisKA#2
203-268 aa · 66 aa · 15.3% of protein
Raw tokenHisKA:203:5.58e-20:268:66:64
3 HATPase_c#3
313-424 aa · 112 aa · 26.0% of protein
Raw tokenHATPase_c:313:4.42e-33:424:112:109
  • Raw architecture: PAS:98:0.00000000000247:194:113:113#HisKA:203:5.58e-20:268:66:64#HATPase_c:313:4.42e-33:424:112:109
  • Domain description: 1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000166595::NZ_AELD01000012.1::G00033
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span268533-270575Genomic interval covered by the local TCS group.
Context group IDGCF_000166595::NZ_AELD01000012.1::G00033
Context members
ESG_RS0107235ESG_RS0107240
Partner locus tags
ESG_RS0107235ESG_RS0107240
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000893580.1Primary protein accession used for annex mappings.
UniProt accessionA0A1V3W2Z6Primary UniProt accession resolved in the annex database.
UniProt IDA0A1V3W2Z6_ECOLXDisplay identifier provided by UniProt.
GO / PubMed7 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagESG_RS0107235Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_AELD01000012.1Sequence record reported by the local genomic context database.
Genomic interval268 533-269 828 nt1 296 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span268 533-270 575 ntGCF_000166595::NZ_AELD01000012.1::G00033

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000166595::NZ_AELD01000012.1::G00033

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AELD01000012.1All displayed genes belong to this local TCS context.
Neighborhood span268 533-270 575 nt2 043 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
268 533 nt270 575 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ESG_RS0107240GCF_000166595#ESG_RS0107240
RROmpR

269 886-270 575 nt · Reverse (-)

RefSeq WP_000113933.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2161294Run 6 · HK · 772 sequences
Representative sequenceGCF_000009565#B21_RS01825Use this link to inspect the representative gene detail.
PFAM architecturePhoR + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2161294

Simplified PFAM architecture for HKOC_2161294

PFAM domain coverage: 360 / 431 aa (83.5%)

1 aa431 aa
PhoR: 6-91 aaPhoRPAS: 99-194 aaPASHisKA: 203-268 aaHisKAHATPase_c: 313-424 aaHATPase_c
PhoRPASHisKAHATPase_c
  • Simplified architecture: PhoR + PAS + HisKA + HATPase_c
  • Raw architecture: PhoR[6-91] | PAS[99-194] | HisKA[203-268] | HATPase_c[313-424]
  • Domain count: 4
  • Matched identifier: HKOC_2161294
  • Positioned domains: PhoR 6-91 ; PAS 99-194 ; HisKA 203-268 ; HATPase_c 313-424
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009565#B21_RS01825

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 913 088 · GCF_000166595
AssemblyASM16659v2 · Contighaploid
Genome composition5 305 843 bp · 50,5% GCEscherichia coli TW11681
Signal transduction countsGenes 68 · HK 32 · RR 35CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key