Gene detail

HMPREF9541_RS10365

Response regulator, unclassified

Escherichia coli MS 116-1 · GCF_000164475

ClassRRTypeunclassifiedLength351 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164475#HMPREF9541_RS10365Stable P2CS identifier used across views.
GenomeGCF_000164475Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterRROC_0477581Run 7 · 2354 sequences · id 100% · cov 80%
External referencesWP_000494233.1 · B7MZF9 · MIST4 HMPREF9541_RS10365RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regHTH_AraC
Protein length351 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage192 / 351 aa (54.7%)Merged over positioned domains only.
Domain description1 Response_reg,2 HTH_AraCSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa351 aa
Response_reg: 4-117 aa (114 aa)1HTH_AraC: 252-292 aa (41 aa)2HTH_AraC: 307-343 aa (37 aa)3
Domain-by-domain annotation3 items
1 Response_reg#1
4-117 aa · 114 aa · 32.5% of protein
Raw tokenResponse_reg:4:3.57e-20:117:115:111
2 HTH_AraC#2
252-292 aa · 41 aa · 11.7% of protein
Raw tokenHTH_AraC:252:0.0000000239:292:41:42
3 HTH_AraC#3
307-343 aa · 37 aa · 10.5% of protein
Raw tokenHTH_AraC:307:0.00000000943:343:37:42
  • Raw architecture: Response_reg:4:3.57e-20:117:115:111#HTH_AraC:252:0.0000000239:292:41:42#HTH_AraC:307:0.00000000943:343:37:42
  • Domain description: 1 Response_reg,2 HTH_AraC
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000164475::NZ_GG773443.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span17085-19419Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9541_02850RefSeq proteinWP_000494233.1
Context group IDGCF_000164475::NZ_GG773443.1::G00020
Context members
HMPREF9541_RS10370HMPREF9541_RS10365
Partner locus tags
HMPREF9541_RS10370HMPREF9541_RS10365
Partner old locus tags
HMPREF9541_02849HMPREF9541_02850
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000494233.1Primary protein accession used for annex mappings.
UniProt accessionB7MZF9Primary UniProt accession resolved in the annex database.
UniProt IDB7MZF9_ECO81Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9541_RS10365Primary locus identifier stored in the genes table.
Old locus tagHMPREF9541_02850Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG773443.1Sequence record reported by the local genomic context database.
Genomic interval18 364-19 419 nt1 056 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span17 085-19 419 ntGCF_000164475::NZ_GG773443.1::G00020

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000164475::NZ_GG773443.1::G00020

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG773443.1All displayed genes belong to this local TCS context.
Neighborhood span17 085-19 419 nt2 335 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
17 085 nt19 419 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9541_RS10370GCF_000164475#HMPREF9541_RS10370
HKClassic

17 085-18 347 nt · Forward (+)

Old locus HMPREF9541_02849RefSeq WP_001329690.1
HMPREF9541_RS10365GCF_000164475#HMPREF9541_RS10365
RRunclassifiedCurrent focus

18 364-19 419 nt · Forward (+)

Old locus HMPREF9541_02850RefSeq WP_000494233.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_0477581Run 7 · RR · 2354 sequences
Representative sequenceGCF_000007445#C_RS21450Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + HTH_AraC + HTH_AraC3 domains in the representative PFAM annotation.

PFAM architecture for RROC_0477581

Simplified PFAM architecture for RROC_0477581

PFAM domain coverage: 190 / 351 aa (54.1%)

1 aa351 aa
Response_reg: 4-116 aaResponse_regResponse_reg: 4-116 aaResponse_regHTH_AraC: 252-292 aaHTH_AraCHTH_AraC: 252-292 aaHTH_AraCHTH_AraC: 308-343 aaHTH_AraCHTH_AraC: 308-343 aaHTH_AraC
Response_regHTH_AraCHTH_AraC
  • Simplified architecture: Response_reg + HTH_AraC + HTH_AraC
  • Raw architecture: Response_reg[4-116] | HTH_AraC[252-292] | HTH_AraC[308-343]
  • Domain count: 3
  • Matched identifier: RROC_0477581
  • Positioned domains: Response_reg 4-116 ; Response_reg 4-116 ; HTH_AraC 252-292 ; HTH_AraC 252-292 ; HTH_AraC 308-343 ; HTH_AraC 308-343
Cluster members and taxonomy
Visualization

Representative gene: GCF_000007445#C_RS21450

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 538 · GCF_000164475
AssemblyASM16447v1 · Scaffoldhaploid
Genome composition4 863 660 bp · 50,5% GCEscherichia coli MS 116-1
Signal transduction countsGenes 64 · HK 31 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key