Gene detail

HMPREF9541_RS00035

Histidine kinase, Classic

Escherichia coli MS 116-1 · GCF_000164475

ClassHKTypeClassicLength598 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164475#HMPREF9541_RS00035Stable P2CS identifier used across views.
GenomeGCF_000164475Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1061602Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_000918051.1 · MIST4 HMPREF9541_RS00035RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PilJHAMPHisKA_3HATPase_c
Protein length598 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage314 / 598 aa (52.5%)Merged over positioned domains only.
Domain description1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa598 aa
PilJ: 35-128 aa (94 aa)1HAMP: 158-225 aa (68 aa)2HisKA_3: 390-453 aa (64 aa)3HATPase_c: 496-583 aa (88 aa)4
Domain-by-domain annotation4 items
1 PilJ#1
35-128 aa · 94 aa · 15.7% of protein
Raw tokenPilJ:35:0.00000000626:128:112:112
2 HAMP#2
158-225 aa · 68 aa · 11.4% of protein
Raw tokenHAMP:158:0.0000000000364:225:69:69
3 HisKA_3#3
390-453 aa · 64 aa · 10.7% of protein
Raw tokenHisKA_3:390:2.01e-17:453:64:68
4 HATPase_c#4
496-583 aa · 88 aa · 14.7% of protein
Raw tokenHATPase_c:496:4.91e-20:583:103:109
  • Raw architecture: PilJ:35:0.00000000626:128:112:112#HAMP:158:0.0000000000364:225:69:69#HisKA_3:390:2.01e-17:453:64:68#HATPase_c:496:4.91e-20:583:103:109
  • Domain description: 1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000164475::NZ_GG773482.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span56264-58703Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9541_05271RefSeq proteinWP_000918051.1
Context group IDGCF_000164475::NZ_GG773482.1::G00002
Context members
HMPREF9541_RS00035HMPREF9541_RS00030
Partner locus tags
HMPREF9541_RS00035HMPREF9541_RS00030
Partner old locus tags
HMPREF9541_05271HMPREF9541_05272
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_000918051.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9541_RS00035Primary locus identifier stored in the genes table.
Old locus tagHMPREF9541_05271Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG773482.1Sequence record reported by the local genomic context database.
Genomic interval56 264-58 060 nt1 797 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span56 264-58 703 ntGCF_000164475::NZ_GG773482.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000164475::NZ_GG773482.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG773482.1All displayed genes belong to this local TCS context.
Neighborhood span56 264-58 703 nt2 440 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
56 264 nt58 703 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9541_RS00030GCF_000164475#HMPREF9541_RS00030
RRNarL

58 053-58 703 nt · Forward (+)

Old locus HMPREF9541_05272RefSeq WP_000070491.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1061602Run 6 · HK · 1 sequences
Representative sequenceGCF_000164475#HMPREF9541_RS00035The current gene is the representative for this cluster.
PFAM architecturePilJ + HAMP + HisKA_3 + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1061602

Simplified PFAM architecture for HKOC_1061602

PFAM domain coverage: 301 / 598 aa (50.3%)

1 aa598 aa
PilJ: 35-129 aaPilJHAMP: 173-224 aaHAMPHisKA_3: 390-453 aaHisKA_3HATPase_c: 496-585 aaHATPase_c
PilJHAMPHisKA_3HATPase_c
  • Simplified architecture: PilJ + HAMP + HisKA_3 + HATPase_c
  • Raw architecture: PilJ[35-129] | HAMP[173-224] | HisKA_3[390-453] | HATPase_c[496-585]
  • Domain count: 4
  • Matched identifier: HKOC_1061602
  • Positioned domains: PilJ 35-129 ; HAMP 173-224 ; HisKA_3 390-453 ; HATPase_c 496-585
Cluster members and taxonomy
Visualization

Representative gene: GCF_000164475#HMPREF9541_RS00035

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 538 · GCF_000164475
AssemblyASM16447v1 · Scaffoldhaploid
Genome composition4 863 660 bp · 50,5% GCEscherichia coli MS 116-1
Signal transduction countsGenes 64 · HK 31 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key