Gene detail

HMPREF9541_RS00620

Histidine kinase, Classic

Escherichia coli MS 116-1 · GCF_000164475

ClassHKTypeClassicLength566 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000164475#HMPREF9541_RS00620Stable P2CS identifier used across views.
GenomeGCF_000164475Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1228909Run 6 · 8700 sequences · id 100% · cov 80%
External referencesWP_001300881.1 · A0ABD7FKJ2 · MIST4 HMPREF9541_RS00620RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PilJHAMPHisKA_3HATPase_c
Protein length566 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage324 / 566 aa (57.2%)Merged over positioned domains only.
Domain description1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa566 aa
PilJ: 31-125 aa (95 aa)1HAMP: 150-224 aa (75 aa)2HisKA_3: 361-424 aa (64 aa)3HATPase_c: 467-556 aa (90 aa)4
Domain-by-domain annotation4 items
1 PilJ#1
31-125 aa · 95 aa · 16.8% of protein
Raw tokenPilJ:31:3.47e-17:125:111:112
2 HAMP#2
150-224 aa · 75 aa · 13.3% of protein
Raw tokenHAMP:150:0.00000000000128:224:75:69
3 HisKA_3#3
361-424 aa · 64 aa · 11.3% of protein
Raw tokenHisKA_3:361:2.27e-17:424:64:68
4 HATPase_c#4
467-556 aa · 90 aa · 15.9% of protein
Raw tokenHATPase_c:467:2.09e-19:556:105:109
  • Raw architecture: PilJ:31:3.47e-17:125:111:112#HAMP:150:0.00000000000128:224:75:69#HisKA_3:361:2.27e-17:424:64:68#HATPase_c:467:2.09e-19:556:105:109
  • Domain description: 1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000164475::NZ_GG773480.1::G00005
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span139095-140795Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9541_05136RefSeq proteinWP_001300881.1
Context group IDGCF_000164475::NZ_GG773480.1::G00005
Context members
HMPREF9541_RS00620
Partner locus tags
HMPREF9541_RS00620
Partner old locus tags
HMPREF9541_05136
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001300881.1Primary protein accession used for annex mappings.
UniProt accessionA0ABD7FKJ2Primary UniProt accession resolved in the annex database.
UniProt IDA0ABD7FKJ2_ECOLXDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9541_RS00620Primary locus identifier stored in the genes table.
Old locus tagHMPREF9541_05136Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG773480.1Sequence record reported by the local genomic context database.
Genomic interval139 095-140 795 nt1 701 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span139 095-140 795 ntGCF_000164475::NZ_GG773480.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000164475::NZ_GG773480.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG773480.1All displayed genes belong to this local TCS context.
Neighborhood span139 095-140 795 nt1 701 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
139 095 nt140 795 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1228909Run 6 · HK · 8700 sequences
Representative sequenceGCF_000005845#b2469Use this link to inspect the representative gene detail.
PFAM architecturePilJ + HAMP + HisKA_3 + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1228909

Simplified PFAM architecture for HKOC_1228909

PFAM domain coverage: 302 / 566 aa (53.4%)

1 aa566 aa
PilJ: 32-127 aaPilJHAMP: 172-223 aaHAMPHisKA_3: 361-424 aaHisKA_3HATPase_c: 467-556 aaHATPase_c
PilJHAMPHisKA_3HATPase_c
  • Simplified architecture: PilJ + HAMP + HisKA_3 + HATPase_c
  • Raw architecture: PilJ[32-127] | HAMP[172-223] | HisKA_3[361-424] | HATPase_c[467-556]
  • Domain count: 4
  • Matched identifier: HKOC_1228909
  • Positioned domains: PilJ 32-127 ; HAMP 172-223 ; HisKA_3 361-424 ; HATPase_c 467-556
Cluster members and taxonomy
Visualization

Representative gene: GCF_000005845#b2469

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 538 · GCF_000164475
AssemblyASM16447v1 · Scaffoldhaploid
Genome composition4 863 660 bp · 50,5% GCEscherichia coli MS 116-1
Signal transduction countsGenes 64 · HK 31 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key