Gene detail

HMPREF9541_RS10090

Histidine kinase, Classic

Escherichia coli MS 116-1 · GCF_000164475

ClassHKTypeClassicLength486 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164475#HMPREF9541_RS10090Stable P2CS identifier used across views.
GenomeGCF_000164475Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1567066Run 6 · 26721 sequences · id 100% · cov 80%
External referencesWP_000735412.1 · D3H1U6 · MIST4 HMPREF9541_RS10090RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PhoQ_SensorHAMPHisKAHATPase_c
Protein length486 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage411 / 486 aa (84.6%)Merged over positioned domains only.
Domain description1 PhoQ_Sensor,1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa486 aa
PhoQ_Sensor: 10-189 aa (180 aa)1HAMP: 195-263 aa (69 aa)2HisKA: 272-330 aa (59 aa)3HATPase_c: 374-476 aa (103 aa)4
Domain-by-domain annotation4 items
1 PhoQ_Sensor#1
10-189 aa · 180 aa · 37.0% of protein
Raw tokenPhoQ_Sensor:10:1.87e-113:189:180:179
2 HAMP#2
195-263 aa · 69 aa · 14.2% of protein
Raw tokenHAMP:195:0.00000000365:263:69:69
3 HisKA#3
272-330 aa · 59 aa · 12.1% of protein
Raw tokenHisKA:272:0.000000441:330:59:64
4 HATPase_c#4
374-476 aa · 103 aa · 21.2% of protein
Raw tokenHATPase_c:374:1.29e-21:476:105:109
  • Raw architecture: PhoQ_Sensor:10:1.87e-113:189:180:179#HAMP:195:0.00000000365:263:69:69#HisKA:272:0.000000441:330:59:64#HATPase_c:374:1.29e-21:476:105:109
  • Domain description: 1 PhoQ_Sensor,1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000164475::NZ_GG773448.1::G00019
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span6707-8838Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9541_02919RefSeq proteinWP_000735412.1
Context group IDGCF_000164475::NZ_GG773448.1::G00019
Context members
HMPREF9541_RS10090HMPREF9541_RS10085
Partner locus tags
HMPREF9541_RS10090HMPREF9541_RS10085
Partner old locus tags
HMPREF9541_02919HMPREF9541_02920
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000735412.1Primary protein accession used for annex mappings.
UniProt accessionD3H1U6Primary UniProt accession resolved in the annex database.
UniProt IDD3H1U6_ECO44Display identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9541_RS10090Primary locus identifier stored in the genes table.
Old locus tagHMPREF9541_02919Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG773448.1Sequence record reported by the local genomic context database.
Genomic interval6 707-8 167 nt1 461 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span6 707-8 838 ntGCF_000164475::NZ_GG773448.1::G00019

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000164475::NZ_GG773448.1::G00019

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG773448.1All displayed genes belong to this local TCS context.
Neighborhood span6 707-8 838 nt2 132 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
6 707 nt8 838 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9541_RS10085GCF_000164475#HMPREF9541_RS10085
RROmpR

8 167-8 838 nt · Reverse (-)

Old locus HMPREF9541_02920RefSeq WP_001265471.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1567066Run 6 · HK · 26721 sequences
Representative sequenceGCF_000005845#b1129Use this link to inspect the representative gene detail.
PFAM architecturePhoQ_Sensor + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1567066

Simplified PFAM architecture for HKOC_1567066

PFAM domain coverage: 280 / 486 aa (57.6%)

1 aa486 aa
PhoQ_Sensor: 10-188 aaPhoQ_SensorHATPase_c: 375-475 aaHATPase_c
PhoQ_SensorHATPase_c
  • Simplified architecture: PhoQ_Sensor + HATPase_c
  • Raw architecture: PhoQ_Sensor[10-188] | HATPase_c[375-475]
  • Domain count: 2
  • Matched identifier: HKOC_1567066
  • Positioned domains: PhoQ_Sensor 10-188 ; HATPase_c 375-475
Cluster members and taxonomy
Visualization

Representative gene: GCF_000005845#b1129

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 538 · GCF_000164475
AssemblyASM16447v1 · Scaffoldhaploid
Genome composition4 863 660 bp · 50,5% GCEscherichia coli MS 116-1
Signal transduction countsGenes 64 · HK 31 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key