Gene detail

HMPREF9541_RS08060

Histidine kinase, Classic

Escherichia coli MS 116-1 · GCF_000164475

ClassHKTypeClassicLength500 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000164475#HMPREF9541_RS08060Stable P2CS identifier used across views.
GenomeGCF_000164475Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1474551Run 6 · 19799 sequences · id 100% · cov 80%
External referencesWP_001295243.1 · A0AAN3ZFT2 · MIST4 HMPREF9541_RS08060RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

MASE1HisKA_3HATPase_c
Protein length500 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage420 / 500 aa (84.0%)Merged over positioned domains only.
Domain description1 MASE1,1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa500 aa
MASE1: 10-277 aa (268 aa)1HisKA_3: 305-370 aa (66 aa)2HATPase_c: 411-496 aa (86 aa)3
Domain-by-domain annotation3 items
1 MASE1#1
10-277 aa · 268 aa · 53.6% of protein
Raw tokenMASE1:10:2.22e-20:277:300:299
2 HisKA_3#2
305-370 aa · 66 aa · 13.2% of protein
Raw tokenHisKA_3:305:0.00000000000000232:370:67:68
3 HATPase_c#3
411-496 aa · 86 aa · 17.2% of protein
Raw tokenHATPase_c:411:0.00000000000000104:496:104:109
  • Raw architecture: MASE1:10:2.22e-20:277:300:299#HisKA_3:305:0.00000000000000232:370:67:68#HATPase_c:411:0.00000000000000104:496:104:109
  • Domain description: 1 MASE1,1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000164475::NZ_GG773459.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2701-4793Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9541_03394RefSeq proteinWP_001295243.1
Context group IDGCF_000164475::NZ_GG773459.1::G00016
Context members
HMPREF9541_RS08065HMPREF9541_RS08060
Partner locus tags
HMPREF9541_RS08065HMPREF9541_RS08060
Partner old locus tags
HMPREF9541_03393HMPREF9541_03394
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001295243.1Primary protein accession used for annex mappings.
UniProt accessionA0AAN3ZFT2Primary UniProt accession resolved in the annex database.
UniProt IDA0AAN3ZFT2_SHIDYDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9541_RS08060Primary locus identifier stored in the genes table.
Old locus tagHMPREF9541_03394Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG773459.1Sequence record reported by the local genomic context database.
Genomic interval3 291-4 793 nt1 503 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 701-4 793 ntGCF_000164475::NZ_GG773459.1::G00016

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000164475::NZ_GG773459.1::G00016

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG773459.1All displayed genes belong to this local TCS context.
Neighborhood span2 701-4 793 nt2 093 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 701 nt4 793 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9541_RS08065GCF_000164475#HMPREF9541_RS08065
RRunclassified

2 701-3 291 nt · Forward (+)

Old locus HMPREF9541_03393RefSeq WP_000633668.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1474551Run 6 · HK · 19799 sequences
Representative sequenceGCF_000005845#b3668Use this link to inspect the representative gene detail.
PFAM architectureMASE1 + HisKA_3 + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1474551

Simplified PFAM architecture for HKOC_1474551

PFAM domain coverage: 418 / 500 aa (83.6%)

1 aa500 aa
MASE1: 12-276 aaMASE1HisKA_3: 305-370 aaHisKA_3HATPase_c: 411-497 aaHATPase_c
MASE1HisKA_3HATPase_c
  • Simplified architecture: MASE1 + HisKA_3 + HATPase_c
  • Raw architecture: MASE1[12-276] | HisKA_3[305-370] | HATPase_c[411-497]
  • Domain count: 3
  • Matched identifier: HKOC_1474551
  • Positioned domains: MASE1 12-276 ; HisKA_3 305-370 ; HATPase_c 411-497
Cluster members and taxonomy
Visualization

Representative gene: GCF_000005845#b3668

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 538 · GCF_000164475
AssemblyASM16447v1 · Scaffoldhaploid
Genome composition4 863 660 bp · 50,5% GCEscherichia coli MS 116-1
Signal transduction countsGenes 64 · HK 31 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key