Gene detail

HMPREF0346_RS18490

Histidine kinase, Classic

Enterococcus faecalis EnGen0297 · GCF_000160155

ClassHKTypeClassicLength856 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000160155#HMPREF0346_RS18490Stable P2CS identifier used across views.
GenomeGCF_000160155Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_0478401Run 6 · 81 sequences · id 100% · cov 80%
External referencesWP_002387713.1 · MIST4 HMPREF0346_RS18490RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

KdpDGAF_3HisKAHATPase_c
Protein length856 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage499 / 856 aa (58.3%)Merged over positioned domains only.
Domain description1 KdpD,1 GAF_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa856 aa
KdpD: 13-221 aa (209 aa)1GAF_3: 502-619 aa (118 aa)2HisKA: 639-702 aa (64 aa)3HATPase_c: 749-856 aa (108 aa)4
Domain-by-domain annotation4 items
1 KdpD#1
13-221 aa · 209 aa · 24.4% of protein
Raw tokenKdpD:13:8.55e-120:221:210:210
2 GAF_3#2
502-619 aa · 118 aa · 13.8% of protein
Raw tokenGAF_3:502:0.0000000962:619:127:129
3 HisKA#3
639-702 aa · 64 aa · 7.5% of protein
Raw tokenHisKA:639:0.0000000000000521:702:64:64
4 HATPase_c#4
749-856 aa · 108 aa · 12.6% of protein
Raw tokenHATPase_c:749:0.000000000000132:856:110:109
  • Raw architecture: KdpD:13:8.55e-120:221:210:210#GAF_3:502:0.0000000962:619:127:129#HisKA:639:0.0000000000000521:702:64:64#HATPase_c:749:0.000000000000132:856:110:109
  • Domain description: 1 KdpD,1 GAF_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000160155::NZ_GG668831.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span25357-28628Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0346_1824RefSeq proteinWP_002387713.1
Context group IDGCF_000160155::NZ_GG668831.1::G00001
Context members
HMPREF0346_RS18485HMPREF0346_RS18490
Partner locus tags
HMPREF0346_RS18485HMPREF0346_RS18490
Partner old locus tags
HMPREF0346_1823HMPREF0346_1824
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_002387713.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0346_RS18490Primary locus identifier stored in the genes table.
Old locus tagHMPREF0346_1824Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG668831.1Sequence record reported by the local genomic context database.
Genomic interval26 058-28 628 nt2 571 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span25 357-28 628 ntGCF_000160155::NZ_GG668831.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000160155::NZ_GG668831.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG668831.1All displayed genes belong to this local TCS context.
Neighborhood span25 357-28 628 nt3 272 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
25 357 nt28 628 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF0346_RS18485GCF_000160155#HMPREF0346_RS18485
RROmpR

25 357-26 046 nt · Reverse (-)

Old locus HMPREF0346_1823RefSeq WP_002358569.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0478401Run 6 · HK · 81 sequences
Representative sequenceGCF_000147595#HMPREF9494_RS06260Use this link to inspect the representative gene detail.
PFAM architectureKdpD + DUF4118 + GAF_3 + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0478401

Simplified PFAM architecture for HKOC_0478401

PFAM domain coverage: 603 / 856 aa (70.4%)

1 aa856 aa
KdpD: 13-221 aaKdpDDUF4118: 374-479 aaDUF4118GAF_3: 502-618 aaGAF_3HisKA: 639-703 aaHisKAHATPase_c: 750-855 aaHATPase_c
KdpDDUF4118GAF_3HisKAHATPase_c
  • Simplified architecture: KdpD + DUF4118 + GAF_3 + HisKA + HATPase_c
  • Raw architecture: KdpD[13-221] | DUF4118[374-479] | GAF_3[502-618] | HisKA[639-703] | HATPase_c[750-855]
  • Domain count: 5
  • Matched identifier: HKOC_0478401
  • Positioned domains: KdpD 13-221 ; DUF4118 374-479 ; GAF_3 502-618 ; HisKA 639-703 ; HATPase_c 750-855
Cluster members and taxonomy
Visualization

Representative gene: GCF_000147595#HMPREF9494_RS06260

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 491 075 · GCF_000160155
AssemblyASM16015v1 · Scaffoldhaploid
Genome composition3 129 930 bp · 37,0% GCEnterococcus faecalis EnGen0297
Signal transduction countsGenes 31 · HK 14 · RR 17CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key