Gene detail

HMPREF0346_RS05025

Histidine kinase, Classic

Enterococcus faecalis EnGen0297 · GCF_000160155

ClassHKTypeClassicLength281 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000160155#HMPREF0346_RS05025Stable P2CS identifier used across views.
GenomeGCF_000160155Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1541175Run 6 · 2646 sequences · id 100% · cov 80%
External referencesWP_002386661.1 · MIST4 HMPREF0346_RS05025RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length281 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage220 / 281 aa (78.3%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa281 aa
HAMP: 1-43 aa (43 aa)1HisKA: 54-120 aa (67 aa)2HATPase_c: 165-274 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
1-43 aa · 43 aa · 15.3% of protein
Raw tokenHAMP:1:0.0000000111:43:43:69
2 HisKA#2
54-120 aa · 67 aa · 23.8% of protein
Raw tokenHisKA:54:0.00000000000000774:120:67:64
3 HATPase_c#3
165-274 aa · 110 aa · 39.1% of protein
Raw tokenHATPase_c:165:1.93e-31:274:110:109
  • Raw architecture: HAMP:1:0.0000000111:43:43:69#HisKA:54:0.00000000000000774:120:67:64#HATPase_c:165:1.93e-31:274:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000160155::NZ_GG668819.1::G00013
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span206453-207298Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0346_0212RefSeq proteinWP_002386661.1
Context group IDGCF_000160155::NZ_GG668819.1::G00013
Context members
HMPREF0346_RS05025
Partner locus tags
HMPREF0346_RS05025
Partner old locus tags
HMPREF0346_0212
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_002386661.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0346_RS05025Primary locus identifier stored in the genes table.
Old locus tagHMPREF0346_0212Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG668819.1Sequence record reported by the local genomic context database.
Genomic interval206 453-207 298 nt846 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span206 453-207 298 ntGCF_000160155::NZ_GG668819.1::G00013

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000160155::NZ_GG668819.1::G00013

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG668819.1All displayed genes belong to this local TCS context.
Neighborhood span206 453-207 298 nt846 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
206 453 nt207 298 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1541175Run 6 · HK · 2646 sequences
Representative sequenceGCF_000007785#EF_RS06080Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1541175

Simplified PFAM architecture for HKOC_1541175

PFAM domain coverage: 227 / 489 aa (46.4%)

1 aa489 aa
HAMP: 200-251 aaHAMPHisKA: 263-327 aaHisKAHATPase_c: 374-483 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[200-251] | HisKA[263-327] | HATPase_c[374-483]
  • Domain count: 3
  • Matched identifier: HKOC_1541175
  • Positioned domains: HAMP 200-251 ; HisKA 263-327 ; HATPase_c 374-483
Cluster members and taxonomy
Visualization

Representative gene: GCF_000007785#EF_RS06080

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 491 075 · GCF_000160155
AssemblyASM16015v1 · Scaffoldhaploid
Genome composition3 129 930 bp · 37,0% GCEnterococcus faecalis EnGen0297
Signal transduction countsGenes 31 · HK 14 · RR 17CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key