Gene detail

FAEPRAM212_RS05135

Histidine kinase, Classic

Faecalibacterium prausnitzii M21/2 · GCF_000154385

ClassHKTypeClassicLength495 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000154385#FAEPRAM212_RS05135Stable P2CS identifier used across views.
GenomeGCF_000154385Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Faecalibacterium
Selected clusterHKOC_1504289Run 6 · 3 sequences · id 100% · cov 80% · representative
External referencesWP_044960090.1 · A0A2A7A395 · MIST4 FAEPRAM212_RS05135RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length495 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage254 / 495 aa (51.3%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa495 aa
HAMP: 189-258 aa (70 aa)1His_kinase: 283-362 aa (80 aa)2HATPase_c: 382-485 aa (104 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
189-258 aa · 70 aa · 14.1% of protein
Raw tokenHAMP:189:0.00000000000000429:258:70:69
2 His_kinase#2
283-362 aa · 80 aa · 16.2% of protein
Raw tokenHis_kinase:283:6.11e-34:362:80:80
3 HATPase_c#3
382-485 aa · 104 aa · 21.0% of protein
Raw tokenHATPase_c:382:1.07e-16:485:106:109
  • Raw architecture: HAMP:189:0.00000000000000429:258:70:69#His_kinase:283:6.11e-34:362:80:80#HATPase_c:382:1.07e-16:485:106:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000154385::NZ_DS483496.1::G00019
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span44240-46515Genomic interval covered by the local TCS group.
Identifiers
Old locus tagFAEPRAM212_00827RefSeq proteinWP_044960090.1
Context group IDGCF_000154385::NZ_DS483496.1::G00019
Context members
FAEPRAM212_RS05135FAEPRAM212_RS05140
Partner locus tags
FAEPRAM212_RS05135FAEPRAM212_RS05140
Partner old locus tags
FAEPRAM212_00827FAEPRAM212_00828
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_044960090.1Primary protein accession used for annex mappings.
UniProt accessionA0A2A7A395Primary UniProt accession resolved in the annex database.
UniProt IDA0A2A7A395_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagFAEPRAM212_RS05135Primary locus identifier stored in the genes table.
Old locus tagFAEPRAM212_00827Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_DS483496.1Sequence record reported by the local genomic context database.
Genomic interval44 240-45 727 nt1 488 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span44 240-46 515 ntGCF_000154385::NZ_DS483496.1::G00019

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000154385::NZ_DS483496.1::G00019

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_DS483496.1All displayed genes belong to this local TCS context.
Neighborhood span44 240-46 515 nt2 276 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
44 240 nt46 515 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

FAEPRAM212_RS05140GCF_000154385#FAEPRAM212_RS05140
RRunclassified

45 724-46 515 nt · Forward (+)

Old locus FAEPRAM212_00828RefSeq WP_005922474.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1504289Run 6 · HK · 3 sequences
Representative sequenceGCF_000154385#FAEPRAM212_RS05135The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1504289

Simplified PFAM architecture for HKOC_1504289

PFAM domain coverage: 232 / 495 aa (46.9%)

1 aa495 aa
HAMP: 205-255 aaHAMPHis_kinase: 284-361 aaHis_kinaseHATPase_c: 382-484 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[205-255] | His_kinase[284-361] | HATPase_c[382-484]
  • Domain count: 3
  • Matched identifier: HKOC_1504289
  • Positioned domains: HAMP 205-255 ; His_kinase 284-361 ; HATPase_c 382-484
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154385#FAEPRAM212_RS05135

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 411 485 · GCF_000154385
AssemblyASM15438v1 · Scaffoldreference genome · haploid
Genome composition3 127 383 bp · 56,0% GCFaecalibacterium prausnitzii M21/2
Signal transduction countsGenes 52 · HK 25 · RR 26CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusFaecalibacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Faecalibacterium

Related genes

Preview from the same derived genome key