1 Response_reg#1
3-113 aa · 111 aa · 48.5% of protein
Raw token
Response_reg:3:3.7e-32:113:112:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9525_RS12565
Response regulator OmpR family
Enterococcus faecium TX0133a04 · GCF_000147235
ClassRRTypeOmpRLength229 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000147235#HMPREF9525_RS12565Stable P2CS identifier used across views.
GenomeGCF_000147235Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
Response_regTrans_reg_C
Protein length229 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage188 / 229 aa (82.1%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 Trans_reg_C#2
150-226 aa · 77 aa · 33.6% of protein
Raw token
Trans_reg_C:150:4.78e-31:226:77:77- Raw architecture: Response_reg:3:3.7e-32:113:112:111#Trans_reg_C:150:4.78e-31:226:77:77
- Domain description: 1 Response_reg,1 Trans_reg_C
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000147235::NZ_GL455051.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span30412-32296Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9525_02705RefSeq proteinWP_002295268.1
Context group ID
GCF_000147235::NZ_GL455051.1::G00018Context members
HMPREF9525_RS12560HMPREF9525_RS12565
Partner locus tags
HMPREF9525_RS12560HMPREF9525_RS12565
Partner old locus tags
HMPREF9525_02704HMPREF9525_02705
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002295268.1Primary protein accession used for annex mappings.
UniProt accessionA0A829F780Primary UniProt accession resolved in the annex database.
UniProt IDA0A829F780_ENTFCDisplay identifier provided by UniProt.
GO / PubMed7 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9525_RS12565Primary locus identifier stored in the genes table.
Old locus tagHMPREF9525_02705Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL455051.1Sequence record reported by the local genomic context database.
Genomic interval31 607-32 296 nt690 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span30 412-32 296 ntGCF_000147235::NZ_GL455051.1::G00018
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000147235::NZ_GL455051.1::G00018Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL455051.1All displayed genes belong to this local TCS context.
Neighborhood span30 412-32 296 nt1 885 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
30 412 nt32 296 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9525_RS12560GCF_000147235#HMPREF9525_RS12560
HKClassic
30 412-31 620 nt · Reverse (-)
HMPREF9525_RS12565GCF_000147235#HMPREF9525_RS12565
RROmpRCurrent focus
31 607-32 296 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000147235#HMPREF9525_RS12565The current gene is the representative for this cluster.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.
PFAM architecture for RROC_1246676
Simplified PFAM architecture for RROC_1246676
PFAM domain coverage: 186 / 229 aa (81.2%)
1 aa229 aa
Response_regTrans_reg_C
- Simplified architecture: Response_reg + Trans_reg_C
- Raw architecture: Response_reg[3-112] | Trans_reg_C[150-225]
- Domain count: 2
- Matched identifier: RROC_1246676
- Positioned domains: Response_reg 3-112 ; Response_reg 3-112 ; Trans_reg_C 150-225 ; Trans_reg_C 150-225
Cluster members and taxonomy
Representative gene: GCF_000147235#HMPREF9525_RS12565
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 523 · GCF_000147235
AssemblyASM14723v1 · Scaffoldhaploid
Genome composition2 922 651 bp · 37,5% GCEnterococcus faecium TX0133a04
Signal transduction countsGenes 34 · HK 16 · RR 18CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key