1 HAMP#1
182-248 aa · 67 aa · 11.2% of protein
Raw token
HAMP:182:4.48e-17:248:67:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9525_RS11935
Histidine kinase, Classic
Enterococcus faecium TX0133a04 · GCF_000147235
ClassHKTypeClassicLength599 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000147235#HMPREF9525_RS11935Stable P2CS identifier used across views.
GenomeGCF_000147235Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HAMPPASHisKAHATPase_c
Protein length599 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage355 / 599 aa (59.3%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa599 aa
Domain-by-domain annotation4 items
2 PAS#2
249-356 aa · 108 aa · 18.0% of protein
Raw token
PAS:249:0.00000000193:356:113:1133 HisKA#3
365-432 aa · 68 aa · 11.4% of protein
Raw token
HisKA:365:7.02e-19:432:68:644 HATPase_c#4
481-592 aa · 112 aa · 18.7% of protein
Raw token
HATPase_c:481:7.37e-32:592:112:109- Raw architecture: HAMP:182:4.48e-17:248:67:69#PAS:249:0.00000000193:356:113:113#HisKA:365:7.02e-19:432:68:64#HATPase_c:481:7.37e-32:592:112:109
- Domain description: 1 HAMP,1 PAS,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000147235::NZ_GL455037.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span8501-11009Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9525_02567RefSeq proteinWP_002321535.1
Context group ID
GCF_000147235::NZ_GL455037.1::G00016Context members
HMPREF9525_RS11935HMPREF9525_RS11940
Partner locus tags
HMPREF9525_RS11935HMPREF9525_RS11940
Partner old locus tags
HMPREF9525_02567HMPREF9525_02568
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_002321535.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9525_RS11935Primary locus identifier stored in the genes table.
Old locus tagHMPREF9525_02567Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL455037.1Sequence record reported by the local genomic context database.
Genomic interval8 501-10 300 nt1 800 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span8 501-11 009 ntGCF_000147235::NZ_GL455037.1::G00016
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000147235::NZ_GL455037.1::G00016Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL455037.1All displayed genes belong to this local TCS context.
Neighborhood span8 501-11 009 nt2 509 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
8 501 nt11 009 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9525_RS11935GCF_000147235#HMPREF9525_RS11935
HKClassicCurrent focus
8 501-10 300 nt · Reverse (-)
HMPREF9525_RS11940GCF_000147235#HMPREF9525_RS11940
RROmpR
10 305-11 009 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000147235#HMPREF9525_RS11935The current gene is the representative for this cluster.
PFAM architectureCache_WalK + HAMP + PAS + HisKA + HATPase_c5 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1057257
Simplified PFAM architecture for HKOC_1057257
PFAM domain coverage: 378 / 599 aa (63.1%)
1 aa599 aa
Cache_WalKHAMPPASHisKAHATPase_c
- Simplified architecture: Cache_WalK + HAMP + PAS + HisKA + HATPase_c
- Raw architecture: Cache_WalK[79-166] | HAMP[199-248] | PAS[250-311] | HisKA[366-432] | HATPase_c[481-591]
- Domain count: 5
- Matched identifier: HKOC_1057257
- Positioned domains: Cache_WalK 79-166 ; HAMP 199-248 ; PAS 250-311 ; HisKA 366-432 ; HATPase_c 481-591
Cluster members and taxonomy
Representative gene: GCF_000147235#HMPREF9525_RS11935
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 523 · GCF_000147235
AssemblyASM14723v1 · Scaffoldhaploid
Genome composition2 922 651 bp · 37,5% GCEnterococcus faecium TX0133a04
Signal transduction countsGenes 34 · HK 16 · RR 18CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key