1 HAMP#1
198-268 aa · 71 aa · 14.2% of protein
Raw token
HAMP:198:0.000000000000542:268:71:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9525_RS02895
Histidine kinase, Classic
Enterococcus faecium TX0133a04 · GCF_000147235
ClassHKTypeClassicLength501 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000147235#HMPREF9525_RS02895Stable P2CS identifier used across views.
GenomeGCF_000147235Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length501 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage249 / 501 aa (49.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa501 aa
Domain-by-domain annotation3 items
2 HisKA#2
273-339 aa · 67 aa · 13.4% of protein
Raw token
HisKA:273:0.00000000000000327:339:67:643 HATPase_c#3
387-497 aa · 111 aa · 22.2% of protein
Raw token
HATPase_c:387:8.61e-28:497:111:109- Raw architecture: HAMP:198:0.000000000000542:268:71:69#HisKA:273:0.00000000000000327:339:67:64#HATPase_c:387:8.61e-28:497:111:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000147235::NZ_GL454930.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span578-2766Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9525_00617RefSeq proteinWP_002298265.1
Context group ID
GCF_000147235::NZ_GL454930.1::G00003Context members
HMPREF9525_RS02895HMPREF9525_RS02900
Partner locus tags
HMPREF9525_RS02895HMPREF9525_RS02900
Partner old locus tags
HMPREF9525_00617HMPREF9525_00618
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002298265.1Primary protein accession used for annex mappings.
UniProt accessionQ3XYQ7Primary UniProt accession resolved in the annex database.
UniProt IDQ3XYQ7_ENTFDDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9525_RS02895Primary locus identifier stored in the genes table.
Old locus tagHMPREF9525_00617Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL454930.1Sequence record reported by the local genomic context database.
Genomic interval578-2 083 nt1 506 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span578-2 766 ntGCF_000147235::NZ_GL454930.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000147235::NZ_GL454930.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL454930.1All displayed genes belong to this local TCS context.
Neighborhood span578-2 766 nt2 189 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
578 nt2 766 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9525_RS02895GCF_000147235#HMPREF9525_RS02895
HKClassicCurrent focus
578-2 083 nt · Reverse (-)
HMPREF9525_RS02900GCF_000147235#HMPREF9525_RS02900
RROmpR
2 080-2 766 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_011316265#BXA52_RS13740Use this link to inspect the representative gene detail.
PFAM architectureArlS_N + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1416543
Simplified PFAM architecture for HKOC_1416543
PFAM domain coverage: 377 / 513 aa (73.5%)
1 aa513 aa
ArlS_NHAMPHisKAHATPase_c
- Simplified architecture: ArlS_N + HAMP + HisKA + HATPase_c
- Raw architecture: ArlS_N[46-193] | HAMP[215-268] | HisKA[274-339] | HATPase_c[388-496]
- Domain count: 4
- Matched identifier: HKOC_1416543
- Positioned domains: ArlS_N 46-193 ; HAMP 215-268 ; HisKA 274-339 ; HATPase_c 388-496
Cluster members and taxonomy
Representative gene: GCF_011316265#BXA52_RS13740
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 523 · GCF_000147235
AssemblyASM14723v1 · Scaffoldhaploid
Genome composition2 922 651 bp · 37,5% GCEnterococcus faecium TX0133a04
Signal transduction countsGenes 34 · HK 16 · RR 18CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key