1 sCache_like#1
35-151 aa · 117 aa · 20.2% of protein
Raw token
sCache_like:35:3.36e-36:151:117:114P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9525_RS03520
Histidine kinase, Classic
Enterococcus faecium TX0133a04 · GCF_000147235
ClassHKTypeClassicLength578 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000147235#HMPREF9525_RS03520Stable P2CS identifier used across views.
GenomeGCF_000147235Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
sCache_likeHisKAHATPase_c
Protein length578 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage286 / 578 aa (49.5%)Merged over positioned domains only.
Domain description1 sCache_like,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa578 aa
Domain-by-domain annotation3 items
2 HisKA#2
360-422 aa · 63 aa · 10.9% of protein
Raw token
HisKA:360:0.0000000000000486:422:63:643 HATPase_c#3
471-576 aa · 106 aa · 18.3% of protein
Raw token
HATPase_c:471:9.09e-31:576:107:109- Raw architecture: sCache_like:35:3.36e-36:151:117:114#HisKA:360:0.0000000000000486:422:63:64#HATPase_c:471:9.09e-31:576:107:109
- Domain description: 1 sCache_like,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000147235::NZ_GL454935.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span8917-11354Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9525_00744RefSeq proteinWP_002297195.1
Context group ID
GCF_000147235::NZ_GL454935.1::G00005Context members
HMPREF9525_RS03515HMPREF9525_RS03520
Partner locus tags
HMPREF9525_RS03515HMPREF9525_RS03520
Partner old locus tags
HMPREF9525_00743HMPREF9525_00744
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002297195.1Primary protein accession used for annex mappings.
UniProt accessionQ3XXG8Primary UniProt accession resolved in the annex database.
UniProt IDQ3XXG8_ENTFDDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9525_RS03520Primary locus identifier stored in the genes table.
Old locus tagHMPREF9525_00744Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL454935.1Sequence record reported by the local genomic context database.
Genomic interval9 618-11 354 nt1 737 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span8 917-11 354 ntGCF_000147235::NZ_GL454935.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000147235::NZ_GL454935.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL454935.1All displayed genes belong to this local TCS context.
Neighborhood span8 917-11 354 nt2 438 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
8 917 nt11 354 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9525_RS03515GCF_000147235#HMPREF9525_RS03515
RROmpR
8 917-9 621 nt · Forward (+)
HMPREF9525_RS03520GCF_000147235#HMPREF9525_RS03520
HKClassicCurrent focus
9 618-11 354 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000147235#HMPREF9525_RS03520The current gene is the representative for this cluster.
PFAM architecturesCache_like + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1172270
Simplified PFAM architecture for HKOC_1172270
PFAM domain coverage: 277 / 578 aa (47.9%)
1 aa578 aa
sCache_likeHisKAHATPase_c
- Simplified architecture: sCache_like + HisKA + HATPase_c
- Raw architecture: sCache_like[38-143] | HisKA[360-423] | HATPase_c[471-577]
- Domain count: 3
- Matched identifier: HKOC_1172270
- Positioned domains: sCache_like 38-143 ; HisKA 360-423 ; HATPase_c 471-577
Cluster members and taxonomy
Representative gene: GCF_000147235#HMPREF9525_RS03520
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 523 · GCF_000147235
AssemblyASM14723v1 · Scaffoldhaploid
Genome composition2 922 651 bp · 37,5% GCEnterococcus faecium TX0133a04
Signal transduction countsGenes 34 · HK 16 · RR 18CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key