Gene detail

HMPREF9525_RS06440

Response regulator, unclassified

Enterococcus faecium TX0133a04 · GCF_000147235

ClassRRTypeunclassifiedLength521 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000147235#HMPREF9525_RS06440Stable P2CS identifier used across views.
GenomeGCF_000147235Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterRROC_0124408Run 7 · 2440 sequences · id 100% · cov 80% · representative
External referencesWP_002288004.1 · Q3XZY4 · MIST4 HMPREF9525_RS06440RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regHTH_AraC
Protein length521 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage197 / 521 aa (37.8%)Merged over positioned domains only.
Domain description1 Response_reg,2 HTH_AraCSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa521 aa
Response_reg: 4-119 aa (116 aa)1HTH_AraC: 420-462 aa (43 aa)2HTH_AraC: 475-512 aa (38 aa)3
Domain-by-domain annotation3 items
1 Response_reg#1
4-119 aa · 116 aa · 22.3% of protein
Raw tokenResponse_reg:4:6.24e-28:119:117:111
2 HTH_AraC#2
420-462 aa · 43 aa · 8.3% of protein
Raw tokenHTH_AraC:420:0.00000213:462:43:42
3 HTH_AraC#3
475-512 aa · 38 aa · 7.3% of protein
Raw tokenHTH_AraC:475:0.0000000105:512:38:42
  • Raw architecture: Response_reg:4:6.24e-28:119:117:111#HTH_AraC:420:0.00000213:462:43:42#HTH_AraC:475:0.0000000105:512:38:42
  • Domain description: 1 Response_reg,2 HTH_AraC
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000147235::NZ_GL454964.1::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span41316-44325Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9525_01383RefSeq proteinWP_002288004.1
Context group IDGCF_000147235::NZ_GL454964.1::G00009
Context members
HMPREF9525_RS06440HMPREF9525_RS06445
Partner locus tags
HMPREF9525_RS06440HMPREF9525_RS06445
Partner old locus tags
HMPREF9525_01383HMPREF9525_01384
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002288004.1Primary protein accession used for annex mappings.
UniProt accessionQ3XZY4Primary UniProt accession resolved in the annex database.
UniProt IDQ3XZY4_ENTFDDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9525_RS06440Primary locus identifier stored in the genes table.
Old locus tagHMPREF9525_01383Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL454964.1Sequence record reported by the local genomic context database.
Genomic interval41 316-42 881 nt1 566 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span41 316-44 325 ntGCF_000147235::NZ_GL454964.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000147235::NZ_GL454964.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL454964.1All displayed genes belong to this local TCS context.
Neighborhood span41 316-44 325 nt3 010 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
41 316 nt44 325 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9525_RS06440GCF_000147235#HMPREF9525_RS06440
RRunclassifiedCurrent focus

41 316-42 881 nt · Reverse (-)

Old locus HMPREF9525_01383RefSeq WP_002288004.1
HMPREF9525_RS06445GCF_000147235#HMPREF9525_RS06445
HKClassic

42 874-44 325 nt · Reverse (-)

Old locus HMPREF9525_01384RefSeq WP_002288002.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_0124408Run 7 · RR · 2440 sequences
Representative sequenceGCF_000147235#HMPREF9525_RS06440The current gene is the representative for this cluster.
PFAM architectureResponse_reg + HTH_182 domains in the representative PFAM annotation.

PFAM architecture for RROC_0124408

Simplified PFAM architecture for RROC_0124408

PFAM domain coverage: 194 / 521 aa (37.2%)

1 aa521 aa
Response_reg: 4-119 aaResponse_regResponse_reg: 4-119 aaResponse_regHTH_18: 435-512 aaHTH_18HTH_18: 435-512 aaHTH_18
Response_regHTH_18
  • Simplified architecture: Response_reg + HTH_18
  • Raw architecture: Response_reg[4-119] | HTH_18[435-512]
  • Domain count: 2
  • Matched identifier: RROC_0124408
  • Positioned domains: Response_reg 4-119 ; Response_reg 4-119 ; HTH_18 435-512 ; HTH_18 435-512
Cluster members and taxonomy
Visualization

Representative gene: GCF_000147235#HMPREF9525_RS06440

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 523 · GCF_000147235
AssemblyASM14723v1 · Scaffoldhaploid
Genome composition2 922 651 bp · 37,5% GCEnterococcus faecium TX0133a04
Signal transduction countsGenes 34 · HK 16 · RR 18CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key