Gene detail

HMPREF9525_RS05220

Response regulator LytTR family

Enterococcus faecium TX0133a04 · GCF_000147235

ClassRRTypeLytTRLength246 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000147235#HMPREF9525_RS05220Stable P2CS identifier used across views.
GenomeGCF_000147235Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterRROC_0769349Run 7 · 671 sequences · id 100% · cov 80% · representative
External referencesWP_002306055.1 · A0A829A4N0 · MIST4 HMPREF9525_RS05220RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regLytTR
Protein length246 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 246 aa (70.3%)Merged over positioned domains only.
Domain description1 Response_reg,1 LytTRSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for HMPREF9525_RS05220
Domain-by-domain annotation2 items
1 Response_reg#1
5-89 aa · 85 aa · 34.6% of protein
Raw tokenResponse_reg:5:0.00000096:89:85:111
2 LytTR#2
141-228 aa · 88 aa · 35.8% of protein
Raw tokenLytTR:141:0.00000000752:228:91:98
  • Raw architecture: Response_reg:5:0.00000096:89:85:111#LytTR:141:0.00000000752:228:91:98
  • Domain description: 1 Response_reg,1 LytTR
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000147235::NZ_GL454953.1::G00007
Group size11 locus tag listed below.
HK / RR0 / 1Counts resolved for the local TCS neighborhood.
Context span2532-3272Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9525_01113RefSeq proteinWP_002306055.1
Context group IDGCF_000147235::NZ_GL454953.1::G00007
Context members
HMPREF9525_RS05220
Partner locus tags
HMPREF9525_RS05220
Partner old locus tags
HMPREF9525_01113
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002306055.1Primary protein accession used for annex mappings.
UniProt accessionA0A829A4N0Primary UniProt accession resolved in the annex database.
UniProt IDA0A829A4N0_ENTFCDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9525_RS05220Primary locus identifier stored in the genes table.
Old locus tagHMPREF9525_01113Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL454953.1Sequence record reported by the local genomic context database.
Genomic interval2 532-3 272 nt741 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 532-3 272 ntGCF_000147235::NZ_GL454953.1::G00007

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000147235::NZ_GL454953.1::G00007

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL454953.1All displayed genes belong to this local TCS context.
Neighborhood span2 532-3 272 nt741 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 532 nt3 272 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_0769349Run 7 · RR · 671 sequences
Representative sequenceGCF_000147235#HMPREF9525_RS05220The current gene is the representative for this cluster.
PFAM architectureResponse_reg + LytTR2 domains in the representative PFAM annotation.

PFAM architecture for RROC_0769349

Simplified PFAM architecture for RROC_0769349

PFAM domain coverage: 198 / 246 aa (80.5%)

1 aa246 aa
Response_reg: 5-110 aaResponse_regResponse_reg: 5-110 aaResponse_regLytTR: 145-236 aaLytTRLytTR: 145-236 aaLytTR
Response_regLytTR
  • Simplified architecture: Response_reg + LytTR
  • Raw architecture: Response_reg[5-110] | LytTR[145-236]
  • Domain count: 2
  • Matched identifier: RROC_0769349
  • Positioned domains: Response_reg 5-110 ; Response_reg 5-110 ; LytTR 145-236 ; LytTR 145-236
Cluster members and taxonomy
Visualization

Representative gene: GCF_000147235#HMPREF9525_RS05220

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 749 523 · GCF_000147235
AssemblyASM14723v1 · Scaffoldhaploid
Genome composition2 922 651 bp · 37,5% GCEnterococcus faecium TX0133a04
Signal transduction countsGenes 34 · HK 16 · RR 18CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key