1 Response_reg#1
4-113 aa · 110 aa · 49.1% of protein
Raw token
Response_reg:4:6.92e-27:113:111:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9525_RS04725
Response regulator OmpR family
Enterococcus faecium TX0133a04 · GCF_000147235
ClassRRTypeOmpRLength224 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000147235#HMPREF9525_RS04725Stable P2CS identifier used across views.
GenomeGCF_000147235Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
Response_regTrans_reg_C
Protein length224 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage184 / 224 aa (82.1%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa224 aa
Domain-by-domain annotation2 items
2 Trans_reg_C#2
148-221 aa · 74 aa · 33.0% of protein
Raw token
Trans_reg_C:148:4.8e-30:221:75:77- Raw architecture: Response_reg:4:6.92e-27:113:111:111#Trans_reg_C:148:4.8e-30:221:75:77
- Domain description: 1 Response_reg,1 Trans_reg_C
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000147235::NZ_GL454948.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span6947-8664Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9525_01001RefSeq proteinWP_002291233.1
Context group ID
GCF_000147235::NZ_GL454948.1::G00006Context members
HMPREF9525_RS04725HMPREF9525_RS04730
Partner locus tags
HMPREF9525_RS04725HMPREF9525_RS04730
Partner old locus tags
HMPREF9525_01001HMPREF9525_01002
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002291233.1Primary protein accession used for annex mappings.
UniProt accessionA0A828ZXW2Primary UniProt accession resolved in the annex database.
UniProt IDA0A828ZXW2_ENTFCDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9525_RS04725Primary locus identifier stored in the genes table.
Old locus tagHMPREF9525_01001Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL454948.1Sequence record reported by the local genomic context database.
Genomic interval6 947-7 621 nt675 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span6 947-8 664 ntGCF_000147235::NZ_GL454948.1::G00006
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000147235::NZ_GL454948.1::G00006Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL454948.1All displayed genes belong to this local TCS context.
Neighborhood span6 947-8 664 nt1 718 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
6 947 nt8 664 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9525_RS04725GCF_000147235#HMPREF9525_RS04725
RROmpRCurrent focus
6 947-7 621 nt · Forward (+)
HMPREF9525_RS04730GCF_000147235#HMPREF9525_RS04730
HKClassic
7 639-8 664 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_031292975#Q3Y14_RS05050Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.
PFAM architecture for RROC_1184028
Simplified PFAM architecture for RROC_1184028
PFAM domain coverage: 184 / 231 aa (79.7%)
1 aa231 aa
Response_regTrans_reg_C
- Simplified architecture: Response_reg + Trans_reg_C
- Raw architecture: Response_reg[4-113] | Trans_reg_C[149-222]
- Domain count: 2
- Matched identifier: RROC_1184028
- Positioned domains: Response_reg 4-113 ; Trans_reg_C 149-222
Cluster members and taxonomy
Representative gene: GCF_031292975#Q3Y14_RS05050
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 749 523 · GCF_000147235
AssemblyASM14723v1 · Scaffoldhaploid
Genome composition2 922 651 bp · 37,5% GCEnterococcus faecium TX0133a04
Signal transduction countsGenes 34 · HK 16 · RR 18CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key