1 HAMP#1
39-107 aa · 69 aa · 19.7% of protein
Raw token
HAMP:39:0.000000000105:107:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SPR_RS00420
Histidine kinase, Classic
Streptococcus pneumoniae R6 · GCF_000007045
ClassHKTypeClassicLength350 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000007045#SPR_RS00420Stable P2CS identifier used across views.
GenomeGCF_000007045Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length350 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage242 / 350 aa (69.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa350 aa
Domain-by-domain annotation3 items
2 HisKA#2
119-180 aa · 62 aa · 17.7% of protein
Raw token
HisKA:119:0.0000000000013:180:62:643 HATPase_c#3
233-343 aa · 111 aa · 31.7% of protein
Raw token
HATPase_c:233:1.64e-32:343:111:109- Raw architecture: HAMP:39:0.000000000105:107:69:69#HisKA:119:0.0000000000013:180:62:64#HATPase_c:233:1.64e-32:343:111:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000007045::NC_003098.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span83838-85585Genomic interval covered by the local TCS group.
Identifiers
Old locus tagspr0077RefSeq proteinWP_000769768.1
Context group ID
GCF_000007045::NC_003098.1::G00001Context members
SPR_RS00415SPR_RS00420
Partner locus tags
SPR_RS00415SPR_RS00420
Partner old locus tags
spr0076spr0077
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000769768.1Primary protein accession used for annex mappings.
UniProt accessionQ8DRK0Primary UniProt accession resolved in the annex database.
UniProt IDQ8DRK0_STRR6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSPR_RS00420Primary locus identifier stored in the genes table.
Old locus tagspr0077Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_003098.1Sequence record reported by the local genomic context database.
Genomic interval84 533-85 585 nt1 053 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span83 838-85 585 ntGCF_000007045::NC_003098.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000007045::NC_003098.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_003098.1All displayed genes belong to this local TCS context.
Neighborhood span83 838-85 585 nt1 748 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
83 838 nt85 585 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
SPR_RS00415GCF_000007045#SPR_RS00415
RROmpR
83 838-84 536 nt · Forward (+)
SPR_RS00420GCF_000007045#SPR_RS00420
HKClassicCurrent focus
84 533-85 585 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000006885#SP_RS00435Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2796907
Simplified PFAM architecture for HKOC_2796907
PFAM domain coverage: 216 / 350 aa (61.7%)
1 aa350 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[63-107] | HisKA[120-179] | HATPase_c[233-343]
- Domain count: 3
- Matched identifier: HKOC_2796907
- Positioned domains: HAMP 63-107 ; HisKA 120-179 ; HATPase_c 233-343
Cluster members and taxonomy
Representative gene: GCF_000006885#SP_RS00435
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 171 101 · GCF_000007045
AssemblyASM704v1 · Complete Genomehaploid
Genome composition2 038 615 bp · 39,5% GCStreptococcus pneumoniae R6
Signal transduction countsGenes 27 · HK 13 · RR 14CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyStreptococcaceaeGenusStreptococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Streptococcaceae7Streptococcus
Related genes
Preview from the same derived genome key