Gene detail

QAC_RS0208735

Histidine kinase, Classic

Clostridioides difficile QCD-66c26 · GCF_000003215

ClassHKTypeClassicLength410 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000003215#QAC_RS0208735Stable P2CS identifier used across views.
GenomeGCF_000003215Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2321203Run 6 · 2099 sequences · id 100% · cov 80%
External referencesWP_004454470.1 · A0A0H3N2C6 · MIST4 QAC_RS0208735RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length410 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage179 / 410 aa (43.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QAC_RS0208735
Domain-by-domain annotation2 items
1 HisKA#1
185-250 aa · 66 aa · 16.1% of protein
Raw tokenHisKA:185:0.000000000186:250:66:64
2 HATPase_c#2
296-408 aa · 113 aa · 27.6% of protein
Raw tokenHATPase_c:296:8.11e-25:408:113:109
  • Raw architecture: HisKA:185:0.000000000186:250:66:64#HATPase_c:296:8.11e-25:408:113:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000003215::NZ_CM000441.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1817287-1819180Genomic interval covered by the local TCS group.
Context group IDGCF_000003215::NZ_CM000441.1::G00028
Context members
QAC_RS0208730QAC_RS0208735
Partner locus tags
QAC_RS0208730QAC_RS0208735
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_004454470.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N2C6Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N2C6_CLODCDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQAC_RS0208735Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CM000441.1Sequence record reported by the local genomic context database.
Genomic interval1 817 948-1 819 180 nt1 233 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 817 287-1 819 180 ntGCF_000003215::NZ_CM000441.1::G00028

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000003215::NZ_CM000441.1::G00028

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CM000441.1All displayed genes belong to this local TCS context.
Neighborhood span1 817 287-1 819 180 nt1 894 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 817 287 nt1 819 180 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QAC_RS0208730GCF_000003215#QAC_RS0208730
RROmpR

1 817 287-1 817 958 nt · Forward (+)

RefSeq WP_009889581.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2321203Run 6 · HK · 2099 sequences
Representative sequenceGCF_004318825#E0R25_RS19155Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2321203

Simplified PFAM architecture for HKOC_2321203

PFAM domain coverage: 178 / 414 aa (43.0%)

1 aa414 aa
HisKA: 189-254 aaHisKAHATPase_c: 301-412 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[189-254] | HATPase_c[301-412]
  • Domain count: 2
  • Matched identifier: HKOC_2321203
  • Positioned domains: HisKA 189-254 ; HATPase_c 301-412
Cluster members and taxonomy
Visualization

Representative gene: GCF_004318825#E0R25_RS19155

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 455 631 · GCF_000003215
AssemblyASM321v1 · Chromosomehaploid
Genome composition4 127 750 bp · 28,5% GCClostridioides difficile QCD-66c26
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key