1 HisKA#1
189-254 aa · 66 aa · 15.9% of protein
Raw token
HisKA:189:0.000000000175:254:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0R25_RS19155
Histidine kinase, Classic
Clostridioides difficile · GCF_004318825
ClassHKTypeClassicLength414 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004318825#E0R25_RS19155Stable P2CS identifier used across views.
GenomeGCF_004318825Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length414 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage179 / 414 aa (43.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
300-412 aa · 113 aa · 27.3% of protein
Raw token
HATPase_c:300:7.93e-25:412:113:109- Raw architecture: HisKA:189:0.000000000175:254:66:64#HATPase_c:300:7.93e-25:412:113:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_004318825::NZ_BIWS01000307.1::G00056
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1-1246Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004318825::NZ_BIWS01000307.1::G00056Context members
E0R25_RS19155
Partner locus tags
E0R25_RS19155
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_307721370.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0R25_RS19155Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIWS01000307.1Sequence record reported by the local genomic context database.
Genomic interval1-1 246 nt1 246 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-1 246 ntGCF_004318825::NZ_BIWS01000307.1::G00056
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004318825::NZ_BIWS01000307.1::G00056Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIWS01000307.1All displayed genes belong to this local TCS context.
Neighborhood span1-1 246 nt1 246 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt1 246 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
E0R25_RS19155GCF_004318825#E0R25_RS19155
HKClassicCurrent focus
1-1 246 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_004318825#E0R25_RS19155The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2321203
Simplified PFAM architecture for HKOC_2321203
PFAM domain coverage: 178 / 414 aa (43.0%)
1 aa414 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[189-254] | HATPase_c[301-412]
- Domain count: 2
- Matched identifier: HKOC_2321203
- Positioned domains: HisKA 189-254 ; HATPase_c 301-412
Cluster members and taxonomy
Representative gene: GCF_004318825#E0R25_RS19155
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004318825
AssemblyASM431882v1 · Scaffoldhaploid
Genome composition4 112 375 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 47CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key