1 dCache_1#1
39-269 aa · 231 aa · 40.2% of protein
Raw token
dCache_1:39:0.00000429:269:237:195P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ACFY5R_RS01050
Histidine kinase, Classic
Mediterraneibacter gnavus · GCF_964271885
ClassHKTypeClassicLength575 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_964271885#ACFY5R_RS01050Stable P2CS identifier used across views.
GenomeGCF_964271885Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Domain signature
Compact overview inferred from the domain field
dCache_1HAMPHis_kinaseHATPase_c
Protein length575 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage478 / 575 aa (83.1%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa575 aa
Domain-by-domain annotation4 items
2 HAMP#2
288-354 aa · 67 aa · 11.7% of protein
Raw token
HAMP:288:0.0000000229:354:67:693 His_kinase#3
371-451 aa · 81 aa · 14.1% of protein
Raw token
His_kinase:371:6.78e-31:451:81:804 HATPase_c#4
471-569 aa · 99 aa · 17.2% of protein
Raw token
HATPase_c:471:0.0000000435:569:108:109- Raw architecture: dCache_1:39:0.00000429:269:237:195#HAMP:288:0.0000000229:354:67:69#His_kinase:371:6.78e-31:451:81:80#HATPase_c:471:0.0000000435:569:108:109
- Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_964271885::NZ_OZ186418.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span220989-224235Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_964271885::NZ_OZ186418.1::G00004Context members
ACFY5R_RS01045ACFY5R_RS01050
Partner locus tags
ACFY5R_RS01045ACFY5R_RS01050
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_101879963.1Primary protein accession used for annex mappings.
UniProt accessionA0A2N5NGC3Primary UniProt accession resolved in the annex database.
UniProt IDA0A2N5NGC3_MEDGNDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagACFY5R_RS01050Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_OZ186418.1Sequence record reported by the local genomic context database.
Genomic interval222 508-224 235 nt1 728 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span220 989-224 235 ntGCF_964271885::NZ_OZ186418.1::G00004
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_964271885::NZ_OZ186418.1::G00004Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_OZ186418.1All displayed genes belong to this local TCS context.
Neighborhood span220 989-224 235 nt3 247 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
220 989 nt224 235 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ACFY5R_RS01045GCF_964271885#ACFY5R_RS01045
RRunclassified
220 989-222 518 nt · Reverse (-)
ACFY5R_RS01050GCF_964271885#ACFY5R_RS01050
HKClassicCurrent focus
222 508-224 235 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_002865435#CDL22_RS11845Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1189024
Simplified PFAM architecture for HKOC_1189024
PFAM domain coverage: 179 / 575 aa (31.1%)
1 aa575 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[371-451] | HATPase_c[471-568]
- Domain count: 2
- Matched identifier: HKOC_1189024
- Positioned domains: His_kinase 371-451 ; HATPase_c 471-568
Cluster members and taxonomy
Representative gene: GCF_002865435#CDL22_RS11845
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 33 038 · GCF_964271885
AssemblyLUMC_Rgna_QRD001 · Complete Genomehaploid
Genome composition3 096 184 bp · 43,0% GCMediterraneibacter gnavus
Signal transduction countsGenes 78 · HK 38 · RR 39CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter
Related genes
Preview from the same derived genome key