Gene detail

FJF66_RS15130

Histidine kinase, Classic

Clostridioides difficile · GCF_901004615

ClassHKTypeClassicLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_901004615#FJF66_RS15130Stable P2CS identifier used across views.
GenomeGCF_901004615Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2081764Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_139627028.1 · MIST4 FJF66_RS15130RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage236 / 440 aa (53.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa440 aa
HAMP: 139-204 aa (66 aa)1HisKA: 219-288 aa (70 aa)2HATPase_c: 336-435 aa (100 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
139-204 aa · 66 aa · 15.0% of protein
Raw tokenHAMP:139:0.000000296:204:66:69
2 HisKA#2
219-288 aa · 70 aa · 15.9% of protein
Raw tokenHisKA:219:0.0000000016:288:70:64
3 HATPase_c#3
336-435 aa · 100 aa · 22.7% of protein
Raw tokenHATPase_c:336:5.17e-24:435:101:109
  • Raw architecture: HAMP:139:0.000000296:204:66:69#HisKA:219:0.0000000016:288:70:64#HATPase_c:336:5.17e-24:435:101:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_901004615::NZ_CAAJVI010000010.1::G00053
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span8091-10075Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA1402369_03000RefSeq proteinWP_139627028.1
Context group IDGCF_901004615::NZ_CAAJVI010000010.1::G00053
Context members
FJF66_RS15125FJF66_RS15130
Partner locus tags
FJF66_RS15125FJF66_RS15130
Partner old locus tags
SAMEA1402369_02999SAMEA1402369_03000
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_139627028.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagFJF66_RS15130Primary locus identifier stored in the genes table.
Old locus tagSAMEA1402369_03000Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAAJVI010000010.1Sequence record reported by the local genomic context database.
Genomic interval8 753-10 075 nt1 323 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span8 091-10 075 ntGCF_901004615::NZ_CAAJVI010000010.1::G00053

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_901004615::NZ_CAAJVI010000010.1::G00053

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAAJVI010000010.1All displayed genes belong to this local TCS context.
Neighborhood span8 091-10 075 nt1 985 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
8 091 nt10 075 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

FJF66_RS15125GCF_901004615#FJF66_RS15125
RROmpR

8 091-8 765 nt · Forward (+)

Old locus SAMEA1402369_02999RefSeq WP_022215892.1
FJF66_RS15130GCF_901004615#FJF66_RS15130
HKClassicCurrent focus

8 753-10 075 nt · Forward (+)

Old locus SAMEA1402369_03000RefSeq WP_139627028.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2081764Run 6 · HK · 1 sequences
Representative sequenceGCF_901004615#FJF66_RS15130The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2081764

Simplified PFAM architecture for HKOC_2081764

PFAM domain coverage: 216 / 440 aa (49.1%)

1 aa440 aa
HAMP: 159-204 aaHAMPHisKA: 220-287 aaHisKAHATPase_c: 335-436 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[159-204] | HisKA[220-287] | HATPase_c[335-436]
  • Domain count: 3
  • Matched identifier: HKOC_2081764
  • Positioned domains: HAMP 159-204 ; HisKA 220-287 ; HATPase_c 335-436
Cluster members and taxonomy
Visualization

Representative gene: GCF_901004615#FJF66_RS15130

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_901004615
Assembly7614_4#73 · Contighaploid
Genome composition4 274 293 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 113 · HK 55 · RR 58CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key