Gene detail

E1255_RS09015

Histidine kinase, Classic

Clostridioides difficile · GCF_900692315

ClassHKTypeClassicLength430 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900692315#E1255_RS09015Stable P2CS identifier used across views.
GenomeGCF_900692315Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2179928Run 6 · 7 sequences · id 100% · cov 80% · representative
External referencesWP_131774986.1 · MIST4 E1255_RS09015RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length430 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage177 / 430 aa (41.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa430 aa
HisKA: 207-272 aa (66 aa)1HATPase_c: 320-430 aa (111 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
207-272 aa · 66 aa · 15.3% of protein
Raw tokenHisKA:207:0.0000000000000423:272:66:64
2 HATPase_c#2
320-430 aa · 111 aa · 25.8% of protein
Raw tokenHATPase_c:320:8.76e-28:430:111:109
  • Raw architecture: HisKA:207:0.0000000000000423:272:66:64#HATPase_c:320:8.76e-28:430:111:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900692315::NZ_CAADEL010000005.1::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1944-3916Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA1710436_01777RefSeq proteinWP_131774986.1
Context group IDGCF_900692315::NZ_CAADEL010000005.1::G00025
Context members
E1255_RS09010E1255_RS09015
Partner locus tags
E1255_RS09010E1255_RS09015
Partner old locus tags
SAMEA1710436_01776SAMEA1710436_01777
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_131774986.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE1255_RS09015Primary locus identifier stored in the genes table.
Old locus tagSAMEA1710436_01777Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAADEL010000005.1Sequence record reported by the local genomic context database.
Genomic interval2 624-3 916 nt1 293 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 944-3 916 ntGCF_900692315::NZ_CAADEL010000005.1::G00025

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900692315::NZ_CAADEL010000005.1::G00025

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAADEL010000005.1All displayed genes belong to this local TCS context.
Neighborhood span1 944-3 916 nt1 973 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 944 nt3 916 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E1255_RS09010GCF_900692315#E1255_RS09010
RROmpR

1 944-2 630 nt · Forward (+)

Old locus SAMEA1710436_01776RefSeq WP_003431898.1
E1255_RS09015GCF_900692315#E1255_RS09015
HKClassicCurrent focus

2 624-3 916 nt · Forward (+)

Old locus SAMEA1710436_01777RefSeq WP_131774986.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2179928Run 6 · HK · 7 sequences
Representative sequenceGCF_900692315#E1255_RS09015The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2179928

Simplified PFAM architecture for HKOC_2179928

PFAM domain coverage: 174 / 430 aa (40.5%)

1 aa430 aa
HisKA: 208-272 aaHisKAHATPase_c: 321-429 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[208-272] | HATPase_c[321-429]
  • Domain count: 2
  • Matched identifier: HKOC_2179928
  • Positioned domains: HisKA 208-272 ; HATPase_c 321-429
Cluster members and taxonomy
Visualization

Representative gene: GCF_900692315#E1255_RS09015

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900692315
Assembly9221_6#40 · Scaffoldhaploid
Genome composition4 364 221 bp · 29,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key