1 HAMP#1
161-238 aa · 78 aa · 16.5% of protein
Raw token
HAMP:161:0.0000000135:238:78:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E1153_RS14250
Histidine kinase, Classic
Clostridioides difficile · GCF_900688555
ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900688555#E1153_RS14250Stable P2CS identifier used across views.
GenomeGCF_900688555Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 474 aa (53.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa474 aa
Domain-by-domain annotation3 items
2 HisKA#2
250-315 aa · 66 aa · 13.9% of protein
Raw token
HisKA:250:0.000000002:315:66:643 HATPase_c#3
365-471 aa · 107 aa · 22.6% of protein
Raw token
HATPase_c:365:2.21e-26:471:107:109- Raw architecture: HAMP:161:0.0000000135:238:78:69#HisKA:250:0.000000002:315:66:64#HATPase_c:365:2.21e-26:471:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_900688555::NZ_CAADAX010000011.1::G00042
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span18423-20558Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA1402364_02857RefSeq proteinWP_021402300.1
Context group ID
GCF_900688555::NZ_CAADAX010000011.1::G00042Context members
E1153_RS14250E1153_RS14255
Partner locus tags
E1153_RS14250E1153_RS14255
Partner old locus tags
SAMEA1402364_02857SAMEA1402364_02858
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021402300.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE1153_RS14250Primary locus identifier stored in the genes table.
Old locus tagSAMEA1402364_02857Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAADAX010000011.1Sequence record reported by the local genomic context database.
Genomic interval18 423-19 847 nt1 425 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span18 423-20 558 ntGCF_900688555::NZ_CAADAX010000011.1::G00042
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_900688555::NZ_CAADAX010000011.1::G00042Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAADAX010000011.1All displayed genes belong to this local TCS context.
Neighborhood span18 423-20 558 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
18 423 nt20 558 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E1153_RS14250GCF_900688555#E1153_RS14250
HKClassicCurrent focus
18 423-19 847 nt · Reverse (-)
E1153_RS14255GCF_900688555#E1153_RS14255
RROmpR
19 866-20 558 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_003597855#DA434_RS02835Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1677594
Simplified PFAM architecture for HKOC_1677594
PFAM domain coverage: 223 / 474 aa (47.0%)
1 aa474 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[188-238] | HisKA[251-315] | HATPase_c[365-471]
- Domain count: 3
- Matched identifier: HKOC_1677594
- Positioned domains: HAMP 188-238 ; HisKA 251-315 ; HATPase_c 365-471
Cluster members and taxonomy
Representative gene: GCF_003597855#DA434_RS02835
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_900688555
Assembly7614_7#46 · Scaffoldhaploid
Genome composition4 416 792 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 113 · HK 52 · RR 60CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key