Gene detail

E1153_RS01205

Histidine kinase, Classic

Clostridioides difficile · GCF_900688555

ClassHKTypeClassicLength972 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_900688555#E1153_RS01205Stable P2CS identifier used across views.
GenomeGCF_900688555Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0311152Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_131736361.1 · MIST4 E1153_RS01205RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_9HisKAHATPase_c
Protein length972 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage284 / 972 aa (29.2%)Merged over positioned domains only.
Domain description1 PAS_9,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa972 aa
PAS_9: 529-629 aa (101 aa)1HisKA: 715-786 aa (72 aa)2HATPase_c: 833-943 aa (111 aa)3
Domain-by-domain annotation3 items
1 PAS_9#1
529-629 aa · 101 aa · 10.4% of protein
Raw tokenPAS_9:529:0.000066:629:101:102
2 HisKA#2
715-786 aa · 72 aa · 7.4% of protein
Raw tokenHisKA:715:0.00000000000000737:786:72:64
3 HATPase_c#3
833-943 aa · 111 aa · 11.4% of protein
Raw tokenHATPase_c:833:2.12e-31:943:111:109
  • Raw architecture: PAS_9:529:0.000066:629:101:102#HisKA:715:0.00000000000000737:786:72:64#HATPase_c:833:2.12e-31:943:111:109
  • Domain description: 1 PAS_9,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_900688555::NZ_CAADAX010000001.1::G00006
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span278557-281475Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA1402364_00247RefSeq proteinWP_131736361.1
Context group IDGCF_900688555::NZ_CAADAX010000001.1::G00006
Context members
E1153_RS01205
Partner locus tags
E1153_RS01205
Partner old locus tags
SAMEA1402364_00247
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_131736361.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE1153_RS01205Primary locus identifier stored in the genes table.
Old locus tagSAMEA1402364_00247Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAADAX010000001.1Sequence record reported by the local genomic context database.
Genomic interval278 557-281 475 nt2 919 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span278 557-281 475 ntGCF_900688555::NZ_CAADAX010000001.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900688555::NZ_CAADAX010000001.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAADAX010000001.1All displayed genes belong to this local TCS context.
Neighborhood span278 557-281 475 nt2 919 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
278 557 nt281 475 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

E1153_RS01205GCF_900688555#E1153_RS01205
HKClassicCurrent focus

278 557-281 475 nt · Forward (+)

Old locus SAMEA1402364_00247RefSeq WP_131736361.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0311152Run 6 · HK · 1 sequences
Representative sequenceGCF_900688555#E1153_RS01205The current gene is the representative for this cluster.
PFAM architecturePAS_8 + PAS_9 + HisKA + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0311152

Simplified PFAM architecture for HKOC_0311152

PFAM domain coverage: 377 / 972 aa (38.8%)

1 aa972 aa
PAS_8: 303-355 aaPAS_8PAS_9: 529-632 aaPAS_9HisKA: 655-691 aaHisKA: 715-786 aaHisKAHATPase_c: 833-943 aaHATPase_c
PAS_8PAS_9HisKAHisKAHATPase_c
  • Simplified architecture: PAS_8 + PAS_9 + HisKA + HisKA + HATPase_c
  • Raw architecture: PAS_8[303-355] | PAS_9[529-632] | HisKA[655-691] | HisKA[715-786] | HATPase_c[833-943]
  • Domain count: 5
  • Matched identifier: HKOC_0311152
  • Positioned domains: PAS_8 303-355 ; PAS_9 529-632 ; HisKA 655-691 ; HisKA 715-786 ; HATPase_c 833-943
Cluster members and taxonomy
Visualization

Representative gene: GCF_900688555#E1153_RS01205

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900688555
Assembly7614_7#46 · Scaffoldhaploid
Genome composition4 416 792 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 113 · HK 52 · RR 60CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key