Gene detail

E1153_RS06425

Histidine kinase, Classic

Clostridioides difficile · GCF_900688555

ClassHKTypeClassicLength321 aaTM0ValidatedNoCompleteYesContexthexad
Gene IDGCF_900688555#E1153_RS06425Stable P2CS identifier used across views.
GenomeGCF_900688555Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2867837Run 6 · 2 sequences · id 100% · cov 80%
External referencesWP_235666860.1 · MIST4 E1153_RS06425RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length321 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage181 / 321 aa (56.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa321 aa
HisKA: 97-164 aa (68 aa)1HATPase_c: 208-320 aa (113 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
97-164 aa · 68 aa · 21.2% of protein
Raw tokenHisKA:97:0.00000000000328:164:68:64
2 HATPase_c#2
208-320 aa · 113 aa · 35.2% of protein
Raw tokenHATPase_c:208:2.75e-31:320:113:109
  • Raw architecture: HisKA:97:0.00000000000328:164:68:64#HATPase_c:208:2.75e-31:320:113:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelhexadGCF_900688555::NZ_CAADAX010000003.1::G00017
Group size66 locus tags listed below.
HK / RR3 / 3Counts resolved for the local TCS neighborhood.
Context span123966-130815Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA1402364_01291RefSeq proteinWP_235666860.1
Context group IDGCF_900688555::NZ_CAADAX010000003.1::G00017
Context members
E1153_RS06405E1153_RS06410E1153_RS06415E1153_RS06420E1153_RS06425E1153_RS06430
Partner locus tags
E1153_RS06405E1153_RS06410E1153_RS06415E1153_RS06420E1153_RS06425E1153_RS06430
Partner old locus tags
SAMEA1402364_01287SAMEA1402364_01288SAMEA1402364_01289SAMEA1402364_01290SAMEA1402364_01291SAMEA1402364_01292

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_235666860.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE1153_RS06425Primary locus identifier stored in the genes table.
Old locus tagSAMEA1402364_01291Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAADAX010000003.1Sequence record reported by the local genomic context database.
Genomic interval129 118-130 083 nt966 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span123 966-130 815 ntGCF_900688555::NZ_CAADAX010000003.1::G00017

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900688555::NZ_CAADAX010000003.1::G00017

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelhexadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAADAX010000003.1All displayed genes belong to this local TCS context.
Neighborhood span123 966-130 815 nt6 850 nt
Members61 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
123 966 nt130 815 nt
Neighborhood gene cards

6 genes in the current local neighborhood.

E1153_RS06405GCF_900688555#E1153_RS06405
HKClassic

123 966-126 518 nt · Forward (+)

Old locus SAMEA1402364_01287RefSeq WP_235666859.1
E1153_RS06410GCF_900688555#E1153_RS06410
RROmpR

126 552-127 250 nt · Forward (+)

Old locus SAMEA1402364_01288RefSeq WP_003439430.1
E1153_RS06415GCF_900688555#E1153_RS06415
HKClassic

127 359-128 207 nt · Forward (+)

Old locus SAMEA1402364_01289RefSeq WP_021376879.1
E1153_RS06420GCF_900688555#E1153_RS06420
RROmpR

128 241-128 939 nt · Forward (+)

Old locus SAMEA1402364_01290RefSeq WP_003439430.1
E1153_RS06425GCF_900688555#E1153_RS06425
HKClassicCurrent focus

129 118-130 083 nt · Forward (+)

Old locus SAMEA1402364_01291RefSeq WP_235666860.1
E1153_RS06430GCF_900688555#E1153_RS06430
RROmpR

130 117-130 815 nt · Forward (+)

Old locus SAMEA1402364_01292RefSeq WP_003439430.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2867837Run 6 · HK · 2 sequences
Representative sequenceGCF_004319825#E0R80_RS20400Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2867837

Simplified PFAM architecture for HKOC_2867837

PFAM domain coverage: 179 / 321 aa (55.8%)

1 aa321 aa
HisKA: 97-164 aaHisKAHATPase_c: 209-319 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[97-164] | HATPase_c[209-319]
  • Domain count: 2
  • Matched identifier: HKOC_2867837
  • Positioned domains: HisKA 97-164 ; HATPase_c 209-319
Cluster members and taxonomy
Visualization

Representative gene: GCF_004319825#E0R80_RS20400

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900688555
Assembly7614_7#46 · Scaffoldhaploid
Genome composition4 416 792 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 113 · HK 52 · RR 60CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key