1 HisKA#1
278-337 aa · 60 aa · 12.1% of protein
Raw token
HisKA:278:0.0000000023:337:60:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E1132_RS11640
Histidine kinase, Classic
Clostridioides difficile · GCF_900688265
ClassHKTypeClassicLength496 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900688265#E1132_RS11640Stable P2CS identifier used across views.
GenomeGCF_900688265Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length496 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 496 aa (33.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa496 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
383-489 aa · 107 aa · 21.6% of protein
Raw token
HATPase_c:383:1.7e-21:489:107:109- Raw architecture: HisKA:278:0.0000000023:337:60:64#HATPase_c:383:1.7e-21:489:107:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_900688265::NZ_CAADAP010000008.1::G00033
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span43068-45240Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA1402371_02334RefSeq proteinWP_133145365.1
Context group ID
GCF_900688265::NZ_CAADAP010000008.1::G00033Context members
E1132_RS11640E1132_RS11645
Partner locus tags
E1132_RS11640E1132_RS11645
Partner old locus tags
SAMEA1402371_02334SAMEA1402371_02335
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_133145365.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE1132_RS11640Primary locus identifier stored in the genes table.
Old locus tagSAMEA1402371_02334Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAADAP010000008.1Sequence record reported by the local genomic context database.
Genomic interval43 068-44 558 nt1 491 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span43 068-45 240 ntGCF_900688265::NZ_CAADAP010000008.1::G00033
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_900688265::NZ_CAADAP010000008.1::G00033Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAADAP010000008.1All displayed genes belong to this local TCS context.
Neighborhood span43 068-45 240 nt2 173 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
43 068 nt45 240 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E1132_RS11640GCF_900688265#E1132_RS11640
HKClassicCurrent focus
43 068-44 558 nt · Reverse (-)
E1132_RS11645GCF_900688265#E1132_RS11645
RROmpR
44 536-45 240 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_900688265#E1132_RS11640The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1503913
Simplified PFAM architecture for HKOC_1503913
PFAM domain coverage: 169 / 496 aa (34.1%)
1 aa496 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[275-337] | HATPase_c[384-489]
- Domain count: 2
- Matched identifier: HKOC_1503913
- Positioned domains: HisKA 275-337 ; HATPase_c 384-489
Cluster members and taxonomy
Representative gene: GCF_900688265#E1132_RS11640
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_900688265
Assembly7614_7#45 · Scaffoldhaploid
Genome composition4 314 422 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key