Gene detail

E4V63_RS12370

Histidine kinase, Classic

Clostridioides difficile · GCF_900687405

ClassHKTypeClassicLength334 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900687405#E4V63_RS12370Stable P2CS identifier used across views.
GenomeGCF_900687405Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2849844Run 6 · 20 sequences · id 100% · cov 80%
External referencesWP_021408060.1 · MIST4 E4V63_RS12370RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length334 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage169 / 334 aa (50.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa334 aa
HisKA: 118-178 aa (61 aa)1HATPase_c: 224-331 aa (108 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
118-178 aa · 61 aa · 18.3% of protein
Raw tokenHisKA:118:0.000000812:178:63:64
2 HATPase_c#2
224-331 aa · 108 aa · 32.3% of protein
Raw tokenHATPase_c:224:3.15e-25:331:108:109
  • Raw architecture: HisKA:118:0.000000812:178:63:64#HATPase_c:224:3.15e-25:331:108:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900687405::NZ_CAACZO010000011.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span87935-89637Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA1022486_02518RefSeq proteinWP_021408060.1
Context group IDGCF_900687405::NZ_CAACZO010000011.1::G00032
Context members
E4V63_RS12365E4V63_RS12370
Partner locus tags
E4V63_RS12365E4V63_RS12370
Partner old locus tags
SAMEA1022486_02517SAMEA1022486_02518
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021408060.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE4V63_RS12370Primary locus identifier stored in the genes table.
Old locus tagSAMEA1022486_02518Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAACZO010000011.1Sequence record reported by the local genomic context database.
Genomic interval88 633-89 637 nt1 005 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span87 935-89 637 ntGCF_900687405::NZ_CAACZO010000011.1::G00032

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900687405::NZ_CAACZO010000011.1::G00032

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAACZO010000011.1All displayed genes belong to this local TCS context.
Neighborhood span87 935-89 637 nt1 703 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
87 935 nt89 637 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E4V63_RS12365GCF_900687405#E4V63_RS12365
RROmpR

87 935-88 609 nt · Forward (+)

Old locus SAMEA1022486_02517RefSeq WP_003436727.1
E4V63_RS12370GCF_900687405#E4V63_RS12370
HKClassicCurrent focus

88 633-89 637 nt · Forward (+)

Old locus SAMEA1022486_02518RefSeq WP_021408060.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2849844Run 6 · HK · 20 sequences
Representative sequenceGCF_000450785#QO7_RS07340Use this link to inspect the representative gene detail.
PFAM architectureHATPase_c1 domain in the representative PFAM annotation.

PFAM architecture for HKOC_2849844

Simplified PFAM architecture for HKOC_2849844

PFAM domain coverage: 108 / 334 aa (32.3%)

1 aa334 aa
HATPase_c: 224-331 aaHATPase_c
HATPase_c
  • Simplified architecture: HATPase_c
  • Raw architecture: HATPase_c[224-331]
  • Domain count: 1
  • Matched identifier: HKOC_2849844
  • Positioned domains: HATPase_c 224-331
Cluster members and taxonomy
Visualization

Representative gene: GCF_000450785#QO7_RS07340

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900687405
Assembly6437_4#10 · Scaffoldhaploid
Genome composition4 057 710 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 94 · HK 45 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key