Gene detail

E4V63_RS01150

Histidine kinase, Classic

Clostridioides difficile · GCF_900687405

ClassHKTypeClassicLength387 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900687405#E4V63_RS01150Stable P2CS identifier used across views.
GenomeGCF_900687405Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2550384Run 6 · 29 sequences · id 100% · cov 80%
External referencesWP_021407975.1 · MIST4 E4V63_RS01150RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length387 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 387 aa (39.0%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa387 aa
HisKA_3: 188-253 aa (66 aa)1HATPase_c: 294-378 aa (85 aa)2
Domain-by-domain annotation2 items
1 HisKA_3#1
188-253 aa · 66 aa · 17.1% of protein
Raw tokenHisKA_3:188:3.93e-20:253:67:68
2 HATPase_c#2
294-378 aa · 85 aa · 22.0% of protein
Raw tokenHATPase_c:294:0.000000000187:378:104:109
  • Raw architecture: HisKA_3:188:3.93e-20:253:67:68#HATPase_c:294:0.000000000187:378:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900687405::NZ_CAACZO010000001.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span248163-249966Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA1022486_00230RefSeq proteinWP_021407975.1
Context group IDGCF_900687405::NZ_CAACZO010000001.1::G00003
Context members
E4V63_RS01150E4V63_RS01155
Partner locus tags
E4V63_RS01150E4V63_RS01155
Partner old locus tags
SAMEA1022486_00230SAMEA1022486_00231
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021407975.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE4V63_RS01150Primary locus identifier stored in the genes table.
Old locus tagSAMEA1022486_00230Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAACZO010000001.1Sequence record reported by the local genomic context database.
Genomic interval248 163-249 326 nt1 164 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span248 163-249 966 ntGCF_900687405::NZ_CAACZO010000001.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900687405::NZ_CAACZO010000001.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAACZO010000001.1All displayed genes belong to this local TCS context.
Neighborhood span248 163-249 966 nt1 804 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
248 163 nt249 966 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E4V63_RS01150GCF_900687405#E4V63_RS01150
HKClassicCurrent focus

248 163-249 326 nt · Forward (+)

Old locus SAMEA1022486_00230RefSeq WP_021407975.1
E4V63_RS01155GCF_900687405#E4V63_RS01155
RRNarL

249 319-249 966 nt · Forward (+)

Old locus SAMEA1022486_00231RefSeq WP_009896181.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2550384Run 6 · HK · 29 sequences
Representative sequenceGCF_000450785#QO7_RS05980Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2550384

Simplified PFAM architecture for HKOC_2550384

PFAM domain coverage: 150 / 387 aa (38.8%)

1 aa387 aa
HisKA_3: 188-252 aaHisKA_3HATPase_c: 294-378 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[188-252] | HATPase_c[294-378]
  • Domain count: 2
  • Matched identifier: HKOC_2550384
  • Positioned domains: HisKA_3 188-252 ; HATPase_c 294-378
Cluster members and taxonomy
Visualization

Representative gene: GCF_000450785#QO7_RS05980

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900687405
Assembly6437_4#10 · Scaffoldhaploid
Genome composition4 057 710 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 94 · HK 45 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key