1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw token
HisKA:449:0.00000000934:514:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E4V63_RS08970
Histidine kinase, Classic
Clostridioides difficile · GCF_900687405
ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_900687405#E4V63_RS08970Stable P2CS identifier used across views.
GenomeGCF_900687405Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa671 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw token
HATPase_c:565:2.85e-30:668:104:109- Raw architecture: HisKA:449:0.00000000934:514:66:64#HATPase_c:565:2.85e-30:668:104:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpentadGCF_900687405::NZ_CAACZO010000007.1::G00024
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span96312-102035Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA1022486_01827RefSeq proteinWP_022619916.1
Context group ID
GCF_900687405::NZ_CAACZO010000007.1::G00024Context members
E4V63_RS08955E4V63_RS08960E4V63_RS08965E4V63_RS08970E4V63_RS08975
Partner locus tags
E4V63_RS08955E4V63_RS08960E4V63_RS08965E4V63_RS08970E4V63_RS08975
Partner old locus tags
SAMEA1022486_01824SAMEA1022486_01825SAMEA1022486_01826SAMEA1022486_01827SAMEA1022486_01828
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_022619916.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE4V63_RS08970Primary locus identifier stored in the genes table.
Old locus tagSAMEA1022486_01827Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAACZO010000007.1Sequence record reported by the local genomic context database.
Genomic interval99 271-101 286 nt2 016 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span96 312-102 035 ntGCF_900687405::NZ_CAACZO010000007.1::G00024
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_900687405::NZ_CAACZO010000007.1::G00024Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAACZO010000007.1All displayed genes belong to this local TCS context.
Neighborhood span96 312-102 035 nt5 724 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
96 312 nt102 035 nt
Neighborhood gene cards
5 genes in the current local neighborhood.
E4V63_RS08955GCF_900687405#E4V63_RS08955
HKClassic
96 312-97 427 nt · Reverse (-)
E4V63_RS08960GCF_900687405#E4V63_RS08960
RROmpR
97 463-98 161 nt · Reverse (-)
E4V63_RS08965GCF_900687405#E4V63_RS08965
RROmpR
98 541-99 221 nt · Reverse (-)
E4V63_RS08970GCF_900687405#E4V63_RS08970
HKClassicCurrent focus
99 271-101 286 nt · Reverse (-)
E4V63_RS08975GCF_900687405#E4V63_RS08975
RROmpR
101 358-102 035 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000450785#QO7_RS16560Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0842605
Simplified PFAM architecture for HKOC_0842605
PFAM domain coverage: 170 / 671 aa (25.3%)
1 aa671 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[450-514] | HATPase_c[563-667]
- Domain count: 2
- Matched identifier: HKOC_0842605
- Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Representative gene: GCF_000450785#QO7_RS16560
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_900687405
Assembly6437_4#10 · Scaffoldhaploid
Genome composition4 057 710 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 94 · HK 45 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key