1 HAMP#1
136-213 aa · 78 aa · 17.4% of protein
Raw token
HAMP:136:0.00000000421:213:78:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
B2C46_RS10440
Histidine kinase, Classic
Clostridioides difficile · GCF_900166015
ClassHKTypeClassicLength449 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900166015#B2C46_RS10440Stable P2CS identifier used across views.
GenomeGCF_900166015Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length449 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage248 / 449 aa (55.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa449 aa
Domain-by-domain annotation3 items
2 HisKA#2
228-290 aa · 63 aa · 14.0% of protein
Raw token
HisKA:228:0.00000000673:290:63:643 HATPase_c#3
340-446 aa · 107 aa · 23.8% of protein
Raw token
HATPase_c:340:3.55e-26:446:107:109- Raw architecture: HAMP:136:0.00000000421:213:78:69#HisKA:228:0.00000000673:290:63:64#HATPase_c:340:3.55e-26:446:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_900166015::NZ_FUSU01000010.1::G00021
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span159815-161950Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA2239381_02112RefSeq proteinWP_330396100.1
Context group ID
GCF_900166015::NZ_FUSU01000010.1::G00021Context members
B2C46_RS10440B2C46_RS10445
Partner locus tags
B2C46_RS10440B2C46_RS10445
Partner old locus tags
SAMEA2239381_02112SAMEA2239381_02113
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_330396100.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagB2C46_RS10440Primary locus identifier stored in the genes table.
Old locus tagSAMEA2239381_02112Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUSU01000010.1Sequence record reported by the local genomic context database.
Genomic interval159 815-161 164 nt1 350 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span159 815-161 950 ntGCF_900166015::NZ_FUSU01000010.1::G00021
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_900166015::NZ_FUSU01000010.1::G00021Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUSU01000010.1All displayed genes belong to this local TCS context.
Neighborhood span159 815-161 950 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
159 815 nt161 950 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
B2C46_RS10440GCF_900166015#B2C46_RS10440
HKClassicCurrent focus
159 815-161 164 nt · Reverse (-)
B2C46_RS10445GCF_900166015#B2C46_RS10445
RROmpR
161 258-161 950 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_003457015#CDIF102860_RS03745Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1977142
Simplified PFAM architecture for HKOC_1977142
PFAM domain coverage: 221 / 449 aa (49.2%)
1 aa449 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[163-213] | HisKA[228-290] | HATPase_c[340-446]
- Domain count: 3
- Matched identifier: HKOC_1977142
- Positioned domains: HAMP 163-213 ; HisKA 228-290 ; HATPase_c 340-446
Cluster members and taxonomy
Representative gene: GCF_003457015#CDIF102860_RS03745
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_900166015
Assembly11670_1#32 · Scaffoldhaploid
Genome composition4 124 166 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 43 · RR 51CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key