Gene detail

B2C46_RS00880

Histidine kinase, Classic

Clostridioides difficile · GCF_900166015

ClassHKTypeClassicLength414 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900166015#B2C46_RS00880Stable P2CS identifier used across views.
GenomeGCF_900166015Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2319814Run 6 · 37 sequences · id 100% · cov 80%
External referencesWP_032547333.1 · MIST4 B2C46_RS00880RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length414 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 414 aa (40.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa414 aa
HisKA: 196-255 aa (60 aa)1HATPase_c: 301-407 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
196-255 aa · 60 aa · 14.5% of protein
Raw tokenHisKA:196:0.000000000901:255:60:64
2 HATPase_c#2
301-407 aa · 107 aa · 25.8% of protein
Raw tokenHATPase_c:301:8.06e-22:407:107:109
  • Raw architecture: HisKA:196:0.000000000901:255:60:64#HATPase_c:301:8.06e-22:407:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900166015::NZ_FUSU01000001.1::G00039
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span182762-184697Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA2239381_00180RefSeq proteinWP_032547333.1
Context group IDGCF_900166015::NZ_FUSU01000001.1::G00039
Context members
B2C46_RS00875B2C46_RS00880
Partner locus tags
B2C46_RS00875B2C46_RS00880
Partner old locus tags
SAMEA2239381_00179SAMEA2239381_00180
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_032547333.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2C46_RS00880Primary locus identifier stored in the genes table.
Old locus tagSAMEA2239381_00180Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUSU01000001.1Sequence record reported by the local genomic context database.
Genomic interval183 453-184 697 nt1 245 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span182 762-184 697 ntGCF_900166015::NZ_FUSU01000001.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900166015::NZ_FUSU01000001.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUSU01000001.1All displayed genes belong to this local TCS context.
Neighborhood span182 762-184 697 nt1 936 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
182 762 nt184 697 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2C46_RS00875GCF_900166015#B2C46_RS00875
RROmpR

182 762-183 466 nt · Forward (+)

Old locus SAMEA2239381_00179RefSeq WP_032547341.1
B2C46_RS00880GCF_900166015#B2C46_RS00880
HKClassicCurrent focus

183 453-184 697 nt · Forward (+)

Old locus SAMEA2239381_00180RefSeq WP_032547333.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2319814Run 6 · HK · 37 sequences
Representative sequenceGCF_000449185#QCW_RS07395Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2319814

Simplified PFAM architecture for HKOC_2319814

PFAM domain coverage: 169 / 414 aa (40.8%)

1 aa414 aa
HisKA: 193-255 aaHisKAHATPase_c: 302-407 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[193-255] | HATPase_c[302-407]
  • Domain count: 2
  • Matched identifier: HKOC_2319814
  • Positioned domains: HisKA 193-255 ; HATPase_c 302-407
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449185#QCW_RS07395

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900166015
Assembly11670_1#32 · Scaffoldhaploid
Genome composition4 124 166 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 43 · RR 51CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key