1 HAMP#1
170-236 aa · 67 aa · 14.2% of protein
Raw token
HAMP:170:0.00000392:236:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
B2B36_RS18445
Histidine kinase, Classic
Clostridioides difficile · GCF_900164705
ClassHKTypeClassicLength471 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900164705#B2B36_RS18445Stable P2CS identifier used across views.
GenomeGCF_900164705Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length471 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage241 / 471 aa (51.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa471 aa
Domain-by-domain annotation3 items
2 HisKA#2
249-315 aa · 67 aa · 14.2% of protein
Raw token
HisKA:249:0.0000000000000203:315:67:643 HATPase_c#3
363-469 aa · 107 aa · 22.7% of protein
Raw token
HATPase_c:363:7.43e-27:469:108:109- Raw architecture: HAMP:170:0.00000392:236:69:69#HisKA:249:0.0000000000000203:315:67:64#HATPase_c:363:7.43e-27:469:108:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_900164705::NZ_FUNT01000014.1::G00057
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span6520-8664Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3374999_03688RefSeq proteinWP_231305334.1
Context group ID
GCF_900164705::NZ_FUNT01000014.1::G00057Context members
B2B36_RS18440B2B36_RS18445
Partner locus tags
B2B36_RS18440B2B36_RS18445
Partner old locus tags
SAMEA3374999_03687SAMEA3374999_03688
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_231305334.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagB2B36_RS18445Primary locus identifier stored in the genes table.
Old locus tagSAMEA3374999_03688Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUNT01000014.1Sequence record reported by the local genomic context database.
Genomic interval7 249-8 664 nt1 416 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span6 520-8 664 ntGCF_900164705::NZ_FUNT01000014.1::G00057
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_900164705::NZ_FUNT01000014.1::G00057Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUNT01000014.1All displayed genes belong to this local TCS context.
Neighborhood span6 520-8 664 nt2 145 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
6 520 nt8 664 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
B2B36_RS18440GCF_900164705#B2B36_RS18440
RROmpR
6 520-7 245 nt · Forward (+)
B2B36_RS18445GCF_900164705#B2B36_RS18445
HKClassicCurrent focus
7 249-8 664 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_900164705#B2B36_RS18445The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1716470
Simplified PFAM architecture for HKOC_1716470
PFAM domain coverage: 172 / 471 aa (36.5%)
1 aa471 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[249-313] | HATPase_c[363-469]
- Domain count: 2
- Matched identifier: HKOC_1716470
- Positioned domains: HisKA 249-313 ; HATPase_c 363-469
Cluster members and taxonomy
Representative gene: GCF_900164705#B2B36_RS18445
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_900164705
Assembly16852_2#27 · Scaffoldhaploid
Genome composition4 178 517 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 51 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key