Gene detail

B2C08_RS00915

Histidine kinase, Classic

Clostridioides difficile · GCF_900164465

ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900164465#B2C08_RS00915Stable P2CS identifier used across views.
GenomeGCF_900164465Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1760920Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_077723189.1 · MIST4 B2C08_RS00915RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage242 / 467 aa (51.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for B2C08_RS00915
Domain-by-domain annotation3 items
1 HAMP#1
166-232 aa · 67 aa · 14.3% of protein
Raw tokenHAMP:166:0.00000393:232:69:69
2 HisKA#2
245-312 aa · 68 aa · 14.6% of protein
Raw tokenHisKA:245:0.0000000000000123:312:68:64
3 HATPase_c#3
359-465 aa · 107 aa · 22.9% of protein
Raw tokenHATPase_c:359:1.27e-26:465:108:109
  • Raw architecture: HAMP:166:0.00000393:232:69:69#HisKA:245:0.0000000000000123:312:68:64#HATPase_c:359:1.27e-26:465:108:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900164465::NZ_FULO01000001.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span208237-210369Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375126_00192RefSeq proteinWP_077723189.1
Context group IDGCF_900164465::NZ_FULO01000001.1::G00030
Context members
B2C08_RS00910B2C08_RS00915
Partner locus tags
B2C08_RS00910B2C08_RS00915
Partner old locus tags
SAMEA3375126_00191SAMEA3375126_00192
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_077723189.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2C08_RS00915Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375126_00192Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FULO01000001.1Sequence record reported by the local genomic context database.
Genomic interval208 966-210 369 nt1 404 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span208 237-210 369 ntGCF_900164465::NZ_FULO01000001.1::G00030

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900164465::NZ_FULO01000001.1::G00030

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FULO01000001.1All displayed genes belong to this local TCS context.
Neighborhood span208 237-210 369 nt2 133 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
208 237 nt210 369 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2C08_RS00910GCF_900164465#B2C08_RS00910
RROmpR

208 237-208 962 nt · Forward (+)

Old locus SAMEA3375126_00191RefSeq WP_004454491.1
B2C08_RS00915GCF_900164465#B2C08_RS00915
HKClassicCurrent focus

208 966-210 369 nt · Forward (+)

Old locus SAMEA3375126_00192RefSeq WP_077723189.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1760920Run 6 · HK · 1 sequences
Representative sequenceGCF_900164465#B2C08_RS00915The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1760920

Simplified PFAM architecture for HKOC_1760920

PFAM domain coverage: 172 / 467 aa (36.8%)

1 aa467 aa
HisKA: 245-309 aaHisKAHATPase_c: 359-465 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-309] | HATPase_c[359-465]
  • Domain count: 2
  • Matched identifier: HKOC_1760920
  • Positioned domains: HisKA 245-309 ; HATPase_c 359-465
Cluster members and taxonomy
Visualization

Representative gene: GCF_900164465#B2C08_RS00915

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900164465
Assembly16780_8#60 · Scaffoldhaploid
Genome composition4 190 617 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 48 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key