Gene detail

A4Y60_RS16580

Histidine kinase, Classic

Clostridioides difficile · GCF_900012035

ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900012035#A4Y60_RS16580Stable P2CS identifier used across views.
GenomeGCF_900012035Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1674775Run 6 · 28 sequences · id 100% · cov 80%
External referencesWP_009892645.1 · A0AB74R864 · MIST4 A4Y60_RS16580RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 474 aa (53.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa474 aa
HAMP: 161-238 aa (78 aa)1HisKA: 250-315 aa (66 aa)2HATPase_c: 365-471 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
161-238 aa · 78 aa · 16.5% of protein
Raw tokenHAMP:161:0.0000000101:238:78:69
2 HisKA#2
250-315 aa · 66 aa · 13.9% of protein
Raw tokenHisKA:250:0.00000000156:315:66:64
3 HATPase_c#3
365-471 aa · 107 aa · 22.6% of protein
Raw tokenHATPase_c:365:2.27e-26:471:107:109
  • Raw architecture: HAMP:161:0.0000000101:238:78:69#HisKA:250:0.00000000156:315:66:64#HATPase_c:365:2.27e-26:471:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900012035::NZ_FAAL01000037.1::G00046
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span17054-19189Genomic interval covered by the local TCS group.
Context group IDGCF_900012035::NZ_FAAL01000037.1::G00046
Context members
A4Y60_RS16575A4Y60_RS16580
Partner locus tags
A4Y60_RS16575A4Y60_RS16580
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009892645.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74R864Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74R864_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagA4Y60_RS16580Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_FAAL01000037.1Sequence record reported by the local genomic context database.
Genomic interval17 765-19 189 nt1 425 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span17 054-19 189 ntGCF_900012035::NZ_FAAL01000037.1::G00046

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900012035::NZ_FAAL01000037.1::G00046

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FAAL01000037.1All displayed genes belong to this local TCS context.
Neighborhood span17 054-19 189 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
17 054 nt19 189 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

A4Y60_RS16575GCF_900012035#A4Y60_RS16575
RROmpR

17 054-17 746 nt · Forward (+)

RefSeq WP_003434748.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1674775Run 6 · HK · 28 sequences
Representative sequenceGCF_000450145#QK3_RS02580Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1674775

Simplified PFAM architecture for HKOC_1674775

PFAM domain coverage: 223 / 474 aa (47.0%)

1 aa474 aa
HAMP: 188-238 aaHAMPHisKA: 251-315 aaHisKAHATPase_c: 365-471 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[188-238] | HisKA[251-315] | HATPase_c[365-471]
  • Domain count: 3
  • Matched identifier: HKOC_1674775
  • Positioned domains: HAMP 188-238 ; HisKA 251-315 ; HATPase_c 365-471
Cluster members and taxonomy
Visualization

Representative gene: GCF_000450145#QK3_RS02580

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 28 over 28 total members. Page 1 / 1.

GCF_000450145#QK3_RS02580 (representative)
QK3_RS02580 · HK · Classic
RefSeq: WP_009892645.1
UniProt: A0AB74R864
GCF_000003215#QAC_RS0202555
QAC_RS0202555 · HK · Classic
RefSeq: WP_021419284.1
GCF_000210455#CD7855_RS02595
CD7855_RS02595 · HK · Classic
RefSeq: WP_021419284.1
GCF_000211235#CDBI1_RS02695
CDBI1_RS02695 · HK · Classic
RefSeq: WP_021419284.1
GCF_003313545#CDIF27638_RS02825
CDIF27638_RS02825 · HK · Classic
RefSeq: WP_021419284.1
GCF_003482035#CDIF28196_RS02820
CDIF28196_RS02820 · HK · Classic
RefSeq: WP_021419284.1
GCF_003597795#DA426_RS17085
DA426_RS17085 · HK · Classic
RefSeq: WP_021419284.1
GCF_003597835#DA432_RS02765
DA432_RS02765 · HK · Classic
RefSeq: WP_021419284.1
GCF_003597915#DA436_RS02755
DA436_RS02755 · HK · Classic
RefSeq: WP_021419284.1
GCF_006380895#DA417_RS18815
DA417_RS18815 · HK · Classic
RefSeq: WP_009892645.1
UniProt: A0AB74R864
GCF_006408435#DA400_RS02880
DA400_RS02880 · HK · Classic
RefSeq: WP_021419284.1
GCF_009730495#FOC31_RS11285
FOC31_RS11285 · HK · Classic
RefSeq: WP_021419284.1
GCF_015352155#ITJ31_RS02745
ITJ31_RS02745 · HK · Classic
RefSeq: WP_021419284.1
GCF_015732555#CDIF27147_RS02755
CDIF27147_RS02755 · HK · Classic
RefSeq: WP_009892645.1
UniProt: A0AB74R864
GCF_020297525#LA361_RS01720
LA361_RS01720 · HK · Classic
RefSeq: WP_021419284.1
GCF_025758165#OGM31_RS02740
OGM31_RS02740 · HK · Classic
RefSeq: WP_009892645.1
UniProt: A0AB74R864
GCF_025758185#OGM27_RS02740
OGM27_RS02740 · HK · Classic
RefSeq: WP_009892645.1
UniProt: A0AB74R864
GCF_025758245#OGM24_RS02740
OGM24_RS02740 · HK · Classic
RefSeq: WP_009892645.1
UniProt: A0AB74R864
GCF_027885775#PGC37_RS02750
PGC37_RS02750 · HK · Classic
RefSeq: WP_021419284.1
GCF_032081255#XC26_RS00760
XC26_RS00760 · HK · Classic
RefSeq: WP_021419284.1
GCF_032081285#XC28_RS04150
XC28_RS04150 · HK · Classic
RefSeq: WP_021419284.1
GCF_032081585#XC43_RS10540
XC43_RS10540 · HK · Classic
RefSeq: WP_021419284.1
GCF_900011945#C4Q38_RS07655
C4Q38_RS07655 · HK · Classic
RefSeq: WP_021419284.1
GCF_900012035#A4Y60_RS16580
A4Y60_RS16580 · HK · Classic
RefSeq: WP_009892645.1
UniProt: A0AB74R864
GCF_900014585#A4Z74_RS15120
A4Z74_RS15120 · HK · Classic
RefSeq: WP_021419284.1
GCF_900096165#DK481_RS18320
DK481_RS18320 · HK · Classic
RefSeq: WP_021419284.1
GCF_900687405#E4V63_RS17745
E4V63_RS17745 · HK · Classic
RefSeq: WP_009892645.1
UniProt: A0AB74R864
GCF_902386365#FX037_RS02145
FX037_RS02145 · HK · Classic
RefSeq: WP_021419284.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900012035
AssemblyPeptoclostridium difficile · Contighaploid
Genome composition4 117 060 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key