1 HAMP#1
76-153 aa · 78 aa · 20.1% of protein
Raw token
HAMP:76:0.00000000565:153:78:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DA436_RS02755
Histidine kinase, Classic
Clostridioides difficile · GCF_003597915
ClassHKTypeClassicLength389 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003597915#DA436_RS02755Stable P2CS identifier used across views.
GenomeGCF_003597915Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length389 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 389 aa (64.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa389 aa
Domain-by-domain annotation3 items
2 HisKA#2
165-230 aa · 66 aa · 17.0% of protein
Raw token
HisKA:165:0.000000000887:230:66:643 HATPase_c#3
280-386 aa · 107 aa · 27.5% of protein
Raw token
HATPase_c:280:9.86e-27:386:107:109- Raw architecture: HAMP:76:0.00000000565:153:78:69#HisKA:165:0.000000000887:230:66:64#HATPase_c:280:9.86e-27:386:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003597915::NZ_CP028530.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span504410-506545Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA436_02755RefSeq proteinWP_021419284.1
Context group ID
GCF_003597915::NZ_CP028530.1::G00005Context members
DA436_RS02750DA436_RS02755
Partner locus tags
DA436_RS02750DA436_RS02755
Partner old locus tags
DA436_02750DA436_02755
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021419284.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDA436_RS02755Primary locus identifier stored in the genes table.
Old locus tagDA436_02755Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP028530.1Sequence record reported by the local genomic context database.
Genomic interval505 376-506 545 nt1 170 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span504 410-506 545 ntGCF_003597915::NZ_CP028530.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003597915::NZ_CP028530.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP028530.1All displayed genes belong to this local TCS context.
Neighborhood span504 410-506 545 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
504 410 nt506 545 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DA436_RS02750GCF_003597915#DA436_RS02750
RROmpR
504 410-505 102 nt · Forward (+)
DA436_RS02755GCF_003597915#DA436_RS02755
HKClassicCurrent focus
505 376-506 545 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000450145#QK3_RS02580Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1674775
Simplified PFAM architecture for HKOC_1674775
PFAM domain coverage: 223 / 474 aa (47.0%)
1 aa474 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[188-238] | HisKA[251-315] | HATPase_c[365-471]
- Domain count: 3
- Matched identifier: HKOC_1674775
- Positioned domains: HAMP 188-238 ; HisKA 251-315 ; HATPase_c 365-471
Cluster members and taxonomy
Representative gene: GCF_000450145#QK3_RS02580
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003597915
AssemblyASM359791v1 · Chromosomehaploid
Genome composition4 174 406 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key