Gene detail

ACIRUQ_RS00900

Histidine kinase, Classic

Eubacterium ramulus · GCF_045002895

ClassHKTypeClassicLength564 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_045002895#ACIRUQ_RS00900Stable P2CS identifier used across views.
GenomeGCF_045002895Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Selected clusterHKOC_1240319Run 6 · 3 sequences · id 100% · cov 80%
External referencesWP_055290399.1 · A0A173U8K7 · MIST4 ACIRUQ_RS00900RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length564 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 564 aa (44.5%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa564 aa
HAMP: 273-342 aa (70 aa)1His_kinase: 358-428 aa (71 aa)2HATPase_c: 448-557 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
273-342 aa · 70 aa · 12.4% of protein
Raw tokenHAMP:273:0.000000000000335:342:70:69
2 His_kinase#2
358-428 aa · 71 aa · 12.6% of protein
Raw tokenHis_kinase:358:4.57e-26:428:71:80
3 HATPase_c#3
448-557 aa · 110 aa · 19.5% of protein
Raw tokenHATPase_c:448:0.000000000000825:557:119:109
  • Raw architecture: HAMP:273:0.000000000000335:342:70:69#His_kinase:358:4.57e-26:428:71:80#HATPase_c:448:0.000000000000825:557:119:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_045002895::NZ_CP173382.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span160462-163660Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACIRUQ_00900RefSeq proteinWP_055290399.1
Context group IDGCF_045002895::NZ_CP173382.1::G00004
Context members
ACIRUQ_RS00895ACIRUQ_RS00900
Partner locus tags
ACIRUQ_RS00895ACIRUQ_RS00900
Partner old locus tags
ACIRUQ_00895ACIRUQ_00900
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_055290399.1Primary protein accession used for annex mappings.
UniProt accessionA0A173U8K7Primary UniProt accession resolved in the annex database.
UniProt IDA0A173U8K7_EUBRADisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagACIRUQ_RS00900Primary locus identifier stored in the genes table.
Old locus tagACIRUQ_00900Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP173382.1Sequence record reported by the local genomic context database.
Genomic interval161 966-163 660 nt1 695 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span160 462-163 660 ntGCF_045002895::NZ_CP173382.1::G00004

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_045002895::NZ_CP173382.1::G00004

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP173382.1All displayed genes belong to this local TCS context.
Neighborhood span160 462-163 660 nt3 199 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
160 462 nt163 660 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ACIRUQ_RS00895GCF_045002895#ACIRUQ_RS00895
RRunclassified

160 462-161 994 nt · Forward (+)

Old locus ACIRUQ_00895RefSeq WP_055290400.1
ACIRUQ_RS00900GCF_045002895#ACIRUQ_RS00900
HKClassicCurrent focus

161 966-163 660 nt · Forward (+)

Old locus ACIRUQ_00900RefSeq WP_055290399.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1240319Run 6 · HK · 3 sequences
Representative sequenceGCF_001406295#ARA08_RS09320Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1240319

Simplified PFAM architecture for HKOC_1240319

PFAM domain coverage: 227 / 564 aa (40.2%)

1 aa564 aa
HAMP: 291-342 aaHAMPHis_kinase: 358-430 aaHis_kinaseHATPase_c: 454-555 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[291-342] | His_kinase[358-430] | HATPase_c[454-555]
  • Domain count: 3
  • Matched identifier: HKOC_1240319
  • Positioned domains: HAMP 291-342 ; His_kinase 358-430 ; HATPase_c 454-555
Cluster members and taxonomy
Visualization

Representative gene: GCF_001406295#ARA08_RS09320

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 39 490 · GCF_045002895
AssemblyASM4500289v1 · Complete Genomereference genome · haploid
Genome composition3 378 009 bp · 43,0% GCEubacterium ramulus
Signal transduction countsGenes 71 · HK 36 · RR 34CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium

Related genes

Preview from the same derived genome key