Gene detail

ACIRUQ_RS00185

Histidine kinase, Classic

Eubacterium ramulus · GCF_045002895

ClassHKTypeClassicLength610 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_045002895#ACIRUQ_RS00185Stable P2CS identifier used across views.
GenomeGCF_045002895Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Selected clusterHKOC_1004920Run 6 · 2 sequences · id 100% · cov 80%
External referencesWP_055290189.1 · A0A173TH86 · MIST4 ACIRUQ_RS00185RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length610 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage449 / 610 aa (73.6%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for ACIRUQ_RS00185
Domain-by-domain annotation4 items
1 dCache_1#1
101-288 aa · 188 aa · 30.8% of protein
Raw tokendCache_1:101:0.0000049:288:196:195
2 HAMP#2
306-375 aa · 70 aa · 11.5% of protein
Raw tokenHAMP:306:0.000000000000974:375:70:69
3 His_kinase#3
390-469 aa · 80 aa · 13.1% of protein
Raw tokenHis_kinase:390:1.15e-27:469:80:80
4 HATPase_c#4
486-596 aa · 111 aa · 18.2% of protein
Raw tokenHATPase_c:486:0.00000000000837:596:111:109
  • Raw architecture: dCache_1:101:0.0000049:288:196:195#HAMP:306:0.000000000000974:375:70:69#His_kinase:390:1.15e-27:469:80:80#HATPase_c:486:0.00000000000837:596:111:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_045002895::NZ_CP173382.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span41932-44953Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACIRUQ_00185RefSeq proteinWP_055290189.1
Context group IDGCF_045002895::NZ_CP173382.1::G00001
Context members
ACIRUQ_RS00185ACIRUQ_RS00190
Partner locus tags
ACIRUQ_RS00185ACIRUQ_RS00190
Partner old locus tags
ACIRUQ_00185ACIRUQ_00190
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_055290189.1Primary protein accession used for annex mappings.
UniProt accessionA0A173TH86Primary UniProt accession resolved in the annex database.
UniProt IDA0A173TH86_EUBRADisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagACIRUQ_RS00185Primary locus identifier stored in the genes table.
Old locus tagACIRUQ_00185Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP173382.1Sequence record reported by the local genomic context database.
Genomic interval41 932-43 764 nt1 833 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span41 932-44 953 ntGCF_045002895::NZ_CP173382.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_045002895::NZ_CP173382.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP173382.1All displayed genes belong to this local TCS context.
Neighborhood span41 932-44 953 nt3 022 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
41 932 nt44 953 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ACIRUQ_RS00185GCF_045002895#ACIRUQ_RS00185
HKClassicCurrent focus

41 932-43 764 nt · Forward (+)

Old locus ACIRUQ_00185RefSeq WP_055290189.1
ACIRUQ_RS00190GCF_045002895#ACIRUQ_RS00190
RRunclassified

43 739-44 953 nt · Forward (+)

Old locus ACIRUQ_00190RefSeq WP_055290188.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1004920Run 6 · HK · 2 sequences
Representative sequenceGCF_001406295#ARA08_RS07320Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1004920

Simplified PFAM architecture for HKOC_1004920

PFAM domain coverage: 241 / 610 aa (39.5%)

1 aa610 aa
HAMP: 324-375 aaHAMPHis_kinase: 390-468 aaHis_kinaseHATPase_c: 488-597 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[324-375] | His_kinase[390-468] | HATPase_c[488-597]
  • Domain count: 3
  • Matched identifier: HKOC_1004920
  • Positioned domains: HAMP 324-375 ; His_kinase 390-468 ; HATPase_c 488-597
Cluster members and taxonomy
Visualization

Representative gene: GCF_001406295#ARA08_RS07320

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 39 490 · GCF_045002895
AssemblyASM4500289v1 · Complete Genomereference genome · haploid
Genome composition3 378 009 bp · 43,0% GCEubacterium ramulus
Signal transduction countsGenes 71 · HK 36 · RR 34CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium

Related genes

Preview from the same derived genome key