Gene detail

ACGAK8_RS09125

Histidine kinase, Classic

Clostridioides difficile · GCF_043107725

ClassHKTypeClassicLength311 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_043107725#ACGAK8_RS09125Stable P2CS identifier used across views.
GenomeGCF_043107725Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2876518Run 6 · 96 sequences · id 100% · cov 80%
External referencesWP_021366293.1 · A0A069AYG3 · MIST4 ACGAK8_RS09125RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length311 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage171 / 311 aa (55.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa311 aa
HisKA: 93-156 aa (64 aa)1HATPase_c: 204-310 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
93-156 aa · 64 aa · 20.6% of protein
Raw tokenHisKA:93:0.0000000617:156:64:64
2 HATPase_c#2
204-310 aa · 107 aa · 34.4% of protein
Raw tokenHATPase_c:204:5.41e-31:310:107:109
  • Raw architecture: HisKA:93:0.0000000617:156:64:64#HATPase_c:204:5.41e-31:310:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_043107725::NZ_JBICPJ010000004.1::G00033
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span220529-222153Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACGAK8_09125RefSeq proteinWP_021366293.1
Context group IDGCF_043107725::NZ_JBICPJ010000004.1::G00033
Context members
ACGAK8_RS09120ACGAK8_RS09125
Partner locus tags
ACGAK8_RS09120ACGAK8_RS09125
Partner old locus tags
ACGAK8_09120ACGAK8_09125
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021366293.1Primary protein accession used for annex mappings.
UniProt accessionA0A069AYG3Primary UniProt accession resolved in the annex database.
UniProt IDA0A069AYG3_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagACGAK8_RS09125Primary locus identifier stored in the genes table.
Old locus tagACGAK8_09125Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBICPJ010000004.1Sequence record reported by the local genomic context database.
Genomic interval221 218-222 153 nt936 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span220 529-222 153 ntGCF_043107725::NZ_JBICPJ010000004.1::G00033

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_043107725::NZ_JBICPJ010000004.1::G00033

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBICPJ010000004.1All displayed genes belong to this local TCS context.
Neighborhood span220 529-222 153 nt1 625 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
220 529 nt222 153 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ACGAK8_RS09120GCF_043107725#ACGAK8_RS09120
RROmpR

220 529-221 221 nt · Forward (+)

Old locus ACGAK8_09120RefSeq WP_009888625.1
ACGAK8_RS09125GCF_043107725#ACGAK8_RS09125
HKClassicCurrent focus

221 218-222 153 nt · Forward (+)

Old locus ACGAK8_09125RefSeq WP_021366293.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2876518Run 6 · HK · 96 sequences
Representative sequenceGCF_000448765#QC5_RS03850Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2876518

Simplified PFAM architecture for HKOC_2876518

PFAM domain coverage: 170 / 311 aa (54.7%)

1 aa311 aa
HisKA: 93-155 aaHisKAHATPase_c: 204-310 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[93-155] | HATPase_c[204-310]
  • Domain count: 2
  • Matched identifier: HKOC_2876518
  • Positioned domains: HisKA 93-155 ; HATPase_c 204-310
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS03850

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 96 total members. Page 1 / 2.

GCF_000448765#QC5_RS03850 (representative)
QC5_RS03850 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_000449705#QGM_RS03970
QGM_RS03970 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_000452265#C673_RS03795
C673_RS03795 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_000452285#C674_RS03790
C674_RS03790 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_000452305#C675_RS03905
C675_RS03905 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_000452325#C676_RS04385
C676_RS04385 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_000473605#QSW_RS04200
QSW_RS04200 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_000586575#Y779_RS0103905
Y779_RS0103905 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_000939295#BN1097_RS05370
BN1097_RS05370 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_001192735#AWU81_RS17590
AWU81_RS17590 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_001263655#AWU80_RS14860
AWU80_RS14860 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_001263675#AWU78_RS15265
AWU78_RS15265 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_001263695#AWU79_RS03305
AWU79_RS03305 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_002301075#BGU05_RS03425
BGU05_RS03425 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_002301105#BGU08_RS02215
BGU08_RS02215 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_002302885#BGV09_RS15115
BGV09_RS15115 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_002303125#BGV22_RS15210
BGV22_RS15210 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_003481905#CDIF29688_RS04710
CDIF29688_RS04710 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_004314925#E0O72_RS11600
E0O72_RS11600 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_004315705#E0P69_RS15780
E0P69_RS15780 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_004315945#E0P54_RS06205
E0P54_RS06205 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_004316725#E0Q14_RS14695
E0Q14_RS14695 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_004317945#E0Q65_RS02125
E0Q65_RS02125 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_004318205#E0Q88_RS11325
E0Q88_RS11325 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_004319125#E0R36_RS03500
E0R36_RS03500 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_007000675#D1N83_RS07465
D1N83_RS07465 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_007000845#D1N73_RS05480
D1N73_RS05480 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_007000915#D1N70_RS08165
D1N70_RS08165 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_007000925#D1N68_RS07320
D1N68_RS07320 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_007000965#D1N69_RS03795
D1N69_RS03795 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_012030135#GSQ49_RS12955
GSQ49_RS12955 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_017310965#JQS20_RS08205
JQS20_RS08205 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_019426605#K1N11_RS10690
K1N11_RS10690 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_021283725#LWE87_RS04420
LWE87_RS04420 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_021283905#LWE93_RS01920
LWE93_RS01920 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_021284005#LWE88_RS05810
LWE88_RS05810 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_024451165#NO136_RS09995
NO136_RS09995 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_025135955#CDIF104450_RS04595
CDIF104450_RS04595 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_025533115#H3U19_RS09230
H3U19_RS09230 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_026337815#OSC44_RS03730
OSC44_RS03730 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_030251305#QQO58_RS13990
QQO58_RS13990 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_030251745#QQO64_RS06365
QQO64_RS06365 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_034188805#SQ131_RS09245
SQ131_RS09245 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_036698425#LFB09_RS09240
LFB09_RS09240 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_036698795#LFB08_RS08855
LFB08_RS08855 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_042876425#ACFYIC_RS05325
ACFYIC_RS05325 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_043107605#ACGAK4_RS10875
ACGAK4_RS10875 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_043107725#ACGAK8_RS09125
ACGAK8_RS09125 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_900008635#A4001_RS03045
A4001_RS03045 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3
GCF_900009405#A4055_RS05235
A4055_RS05235 · HK · Classic
RefSeq: WP_021366293.1
UniProt: A0A069AYG3

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_043107725
AssemblyASM4310772v1 · Contighaploid
Genome composition4 220 623 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key