Gene detail

OSC44_RS03730

Histidine kinase, Classic

Clostridioides difficile · GCF_026337815

ClassHKTypeClassicLength311 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_026337815#OSC44_RS03730Stable P2CS identifier used across views.
GenomeGCF_026337815Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2876518Run 6 · 96 sequences · id 100% · cov 80%
External referencesWP_021366293.1 · A0A069AYG3 · MIST4 OSC44_RS03730RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length311 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage171 / 311 aa (55.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa311 aa
HisKA: 93-156 aa (64 aa)1HATPase_c: 204-310 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
93-156 aa · 64 aa · 20.6% of protein
Raw tokenHisKA:93:0.0000000617:156:64:64
2 HATPase_c#2
204-310 aa · 107 aa · 34.4% of protein
Raw tokenHATPase_c:204:5.41e-31:310:107:109
  • Raw architecture: HisKA:93:0.0000000617:156:64:64#HATPase_c:204:5.41e-31:310:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_026337815::NZ_JAPKMC010000016.1::G00039
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span134872-136496Genomic interval covered by the local TCS group.
Identifiers
Old locus tagOSC44_03735RefSeq proteinWP_021366293.1
Context group IDGCF_026337815::NZ_JAPKMC010000016.1::G00039
Context members
OSC44_RS03725OSC44_RS03730
Partner locus tags
OSC44_RS03725OSC44_RS03730
Partner old locus tags
OSC44_03730OSC44_03735
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021366293.1Primary protein accession used for annex mappings.
UniProt accessionA0A069AYG3Primary UniProt accession resolved in the annex database.
UniProt IDA0A069AYG3_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagOSC44_RS03730Primary locus identifier stored in the genes table.
Old locus tagOSC44_03735Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAPKMC010000016.1Sequence record reported by the local genomic context database.
Genomic interval135 561-136 496 nt936 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span134 872-136 496 ntGCF_026337815::NZ_JAPKMC010000016.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_026337815::NZ_JAPKMC010000016.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAPKMC010000016.1All displayed genes belong to this local TCS context.
Neighborhood span134 872-136 496 nt1 625 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
134 872 nt136 496 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

OSC44_RS03725GCF_026337815#OSC44_RS03725
RROmpR

134 872-135 564 nt · Forward (+)

Old locus OSC44_03730RefSeq WP_009888625.1
OSC44_RS03730GCF_026337815#OSC44_RS03730
HKClassicCurrent focus

135 561-136 496 nt · Forward (+)

Old locus OSC44_03735RefSeq WP_021366293.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2876518Run 6 · HK · 96 sequences
Representative sequenceGCF_000448765#QC5_RS03850Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2876518

Simplified PFAM architecture for HKOC_2876518

PFAM domain coverage: 170 / 311 aa (54.7%)

1 aa311 aa
HisKA: 93-155 aaHisKAHATPase_c: 204-310 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[93-155] | HATPase_c[204-310]
  • Domain count: 2
  • Matched identifier: HKOC_2876518
  • Positioned domains: HisKA 93-155 ; HATPase_c 204-310
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS03850

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_026337815
AssemblyASM2633781v1 · Contighaploid
Genome composition4 193 628 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key